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Table 1 Sequence features associated with strand selection in human and fly miRNAs

From: Sequence features associated with microRNA strand selection in humans and flies

    Human Fly
All annotated miRNA and new microRNA*   First nuclotide U (36%) U (51%)
   Purine or Pyrimidine bias No No
Strand-biased miRNA Selected strand First nucleotide U (79%) U (80%)
   Purine bias Yes No
  Excluded strand First nucleotide C (76%) C (37%) G (27%)
   Pyrimidine bias Yes No
   GC basepair 25/33 (76%) 15/30 (50%)