Table 1 Functional annotation of shGATA3-regulated genes at 48 h

48 h shGATA3 induced

Chaperone

2.3 E-5

9 out 174

CMT2L, CANX, HSPA9B, HYOUN1, PTGES3, TIMM9, PFDN2, TRAP1, TXNDC4

TGFb signaling

2.1 E-5

7 out 174

TGIF1, TSC22D1, TGFBR1, INHBE, SMAD4, ID1, E2F5

Phosphatase activity

5.3 E-4

3 out 174

UBLCP1, DUSP1, PTPN12

Response to stress

5.3 E-4

14 out 174

DUSP1, EGR1, CMT2L, HSPA9B, HYOUN1, DDIT3, PRNP, SFPQ, NFATC3, SYVN1, TRAP1, ACVRL1, NCR3, HBEGF

RNA metabolic process

8.7 E-3

18 out 174

DDIT3, PPP2R1B, ELL2, EGR1, NFATC3, SFPQ, E2F5, ID1, NFT3, TSC22D1, ZNF146, SF3B14, WDSOF1, ZNF238, ZFP3, CGGBP1, SMAD4, HMGN2

48 h shGATA3 repressed

Cytoplasm

2.2 E-3

39 out 92

*