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Table 2 Promoter analysis of the IR-responding genes in shGATA3 cells at 48 h.

From: GATA3 is a master regulator of the transcriptional response to low-dose ionizing radiation in human keratinocytes

 

Induced

Repressed

Random sample

GATA3 sites/promoter

0.31 +/- 0.02

0.72 +/- 0.08

0.28 +/- 0.03

  1. Mean number of putative GATA3 binding sites in the promoter sequences (-750, +250) of the 30 most induced and 30 most repressed genes in shGATA3 cells. The mean number of putative GATA3 binding sites is indicated. As a control, a random sample of 50 non-responding genes was also analyzed.