Figure 1
From: The relationship between the evolution of microRNA targets and the length of their UTRs
The relation between the number of regulatory miRNAs and the protein evolutionary rate. (a, b) The evolutionary rates of proteins in human (a) and mouse (b) are estimated as the Ka/Ks ratios using the other organism as reference. The number of regulatory miRNAs is calculated by counting miRNAs that have at least one target site within the 3'UTR of a gene. The red lines show the smoothed relation between the two quantities estimated by LOESS method. ρ indicates Spearman correlation coefficient. (c) Correlation between the number of regulatory miRNAs and protein evolution rate using various species as references. miRNA binding sites are based on PITA predictions.