Figure 2

Nucleotide sequence of the 5' upstream region (GenBank accession No. AY878328) of the bovine osteopontin gene SPP1. The 5' region is indicated in uppercase letters, and position +1 (translation initiation codon) is indicated in italic uppercase letters until position *1 (translation termination codon). SNPs are in bold. Putative binding sites (found with http://motif.genome.jp) are shown in grey or underlined when co-localized: octamer factor 1 = Oct-1; TCF11/KCR-F1/Nrf1 homodimers = TCF11; LyF-1 = Lyf-1; c-Myb = c-Myb; stimulating protein 1 = SP1; stress-response element = STRE; AP-1 binding site = AP-1; activator protein 4 = AP-4; IKAROS family zinc finger 1 (Ikaros) = IKZF1; IKAROS family zinc finger 2 (Helios) = IKZF2; nuclear factor of activated T-cells = NF-AT; CRE-binding protein 1/c-Jun heterodimer = CRE-BP; signal transducers and activators of transcription = STATx; C/EBPalpha CCAAT/enhancer binding protein alpha = CCAAT; GATA-binding factor 1 = GATA-1; GATA-binding factor 2 = GATA-2; GATA-binding factor 3 = GATA-3; interferon-stimulated response element = ISRE; activating transcription factor = ATF.