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Table 3 Processed/duplicated pseudogenes

From: Comprehensive analysis of the pseudogenes of glycolytic enzymes in vertebrates: the anomalously high number of GAPDH pseudogenes highlights a recent burst of retrotrans-positional activity

  Human Chimp Mouse Rat Chicken Zebrafish Pufferfish Fruitfly Worm
HK 1/0 [4] 1/2 0/1 [3] - [3] 0/2 - - - -
GPI - [1] - 1/0 [1] - [1] - - - - -
PFK - [3] - - [3] - [3] - 0/1 - - -
ALDO 1/1 [3] 1/1 11/0 [2] 7/0 [3] 0/1 - - - -
TPI 3/0 [1] 2/1 6/1 [1] 3/1 [1] - - - - -
GAPDH 60/2 [2] 47/3 285/46 [2] 329/35 [2] 0/1 - - - -
PGK 1/1 [2] 1/2 2/0 [2] 12/0 [1] - - - - -
PGM 12/0 [2] 13/1 9/0 [2] 3/0 [2] - - - - -
ENO 1/0 [3] 1/2 12/1 [3] 36/3 [3] - - - - -
PK 2/0 [2] 3/0 10/3 [2] 4/1 [1] - - - - -
LDH 10/2 [3] 9/1 27/7 [3] 25/4 [3] - - - - -
Total 97 91 422 463 4 1 0 0 0
  1. Numbers of pseudgenes (processed/duplicated) and [known parent gene isozymes] for each glycolytic enzyme. The numbers of known parent gene isozymes are shown only for human, mouse, and rat because they constitute the most completely annotated genomes in ENSEMBL. A dash '-' indicates that there are no processed or duplicated pseudogenes derived from a particular enzyme in a particular vertebrate genome. The chicken, zebrafish, pufferfish, fruitfly, and worm genomes contain very few or no pseudogenes, the human and chimpanzee genomes a moderate number, and the mouse and rat genomes significantly more. The pseudogene copy number for GAPDH far outnumbers those of any other glycolytic enzyme. Abbreviations: HK, hexokinase; GPI, glucose-6-phosphate isomerase; PFK, 6-phosphofructokinase; ALDO, aldolase; TPI, triose-phosphate isomerase; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; PGK, phosphoglycerate kinase; PGM, phosphoglycerate mutase; ENO, enolase; PK, pyruvate kinase; LDH, lactate dehydrogenase.