A new procedure for determining the genetic basis of a physiological process in a non-model species, illustrated by cold induced angiogenesis in the carp

Table 4 A selection of cold induced angiogenic genes predicted in this work

Gene	Accession	Gene product
APOE	NP_000032	apolipoprotein E
FN1	NP_997647	fibronectin 1
GRN	NP_002078	granulin
HMGB1	NP_002119	high-mobility group box 1
HSPG2	NP_005520	heparan sulfate proteoglycan 2
ITGAL	NP_002200	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
MAPK1	NP_002736	mitogen-activated protein kinase 1
MMP9	NP_004985	matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase)
NCL	NP_005372	nucleolin
PLAUR	NP_002650	plasminogen activator, urokinase receptor
RHOA	NP_001655	ras homolog gene family, member A
SOD2	NP_001019636	superoxide dismutase 2, mitochondrial

From the 135 putative angiogenic genes up regulated due to cold temperatures, 12 genes considered biologically interesting in terms of angiogenesis are listed. The four highlighted in bold are reviewed in the text.

ISSN: 1471-2164