Figure 2

Analysis of microarray data of Trichuris infected gut tissue with either the E isolate or S isolate shown in Venn Diagrams and scatter plots. PPLR values were calculated for E isolated-infected gut tissue compared to naïve (uninfected) gut tissue (EvN), S isolated-infected gut tissue compared to naïve gut tissue (SvN) and S isolated-infected gut tissue compared to E isolate-infected gut tissue (SvE). Distribution of probe sets with a PPLR value greater than 0.999 (A), PPLR less than 0.001 (B) and PPLR greater than 0.999 and/or less than 0.001 (C) in any one of the three comparisons (EvN, SvN or SvE) are shown in Venn diagrams. The scatter plot (D) shows the average log₂-fold changes in probe set expression in gut tissue from E isolate-infected C57BL/6 mice at day 7 compared to that from uninfected C57BL/6 mice (x axis) versus the average log₂-fold changes in probe set expression in gut tissue from S isolate C57BL/6 mice at day 7 compared to that from uninfected C57BL/6 mice (y axis). Gut tissue was pooled from five individual animals within a group, and three independent infection experiments were run. The average log₂-fold changes presented represent values calculated from all three infection experiments.