Figure 3

Clusters, profiles and Gene Ontology groupings of the 409 probe sets that had a PPLR value greater than 0.999 and/or less than 0.001 in at least one of the three comparisons (EvN, SvN or SvE). A: Flow chart showing method of generating the clusters from the probe sets. B: The 409 genes were assigned to one of six distinct clusters using k-means clustering algorithms. Data for each cluster are represented with a z-transformed Eisen colour plot with the number of genes in each cluster shown. Red and green indicate positive and negative change from zero, respectively, with colour intensity indicating the degree of deviation. Profiles of the z-transformed data (for each probe set, the mean set to 0 and SD to 1) for each of the experimental groups are shown next to the Eisen plot. The most significantly overrepresented Gene Ontology terms are then shown for the genes within each cluster. C: Expanded version of cluster C indicating the 43 probe sets, showing probe set number, name and symbol along with Eisen plot.