Figure 4From: Hepatic gene expression profiling reveals protective responses in Atlantic salmon vaccinated against furunculosisSignal transducers and regulators of gene expression. The figure shows expression changes indicative of recruitment and migration of immune cells. A. Real-time qPCR versus microarray analyses. Data for qPCR are ΔΔCt ± SE of 10 HR and 10 LR versus 8 fish in the unchallenged control and data for microarray are mean log2-ER ± SE of 6 HR fish hybridized to a pooled sample of 10 LR fish. Differences between HR and LR determined with microarrays and qPCR are shown. Different capital letters (A, B) denote a difference between challenged fish (HR and LR) while small letters (a, b) denote a difference between challenged and control fish (ANOVA, P < 0.05). NFKB1 - nuclear factor NF-kappa-B p105 subunit, NFKBIA - NF-kappa-B inhibitor alpha, CREBBP - CREB-binding protein, YY1 - YY1 transcription factor. B. Microarray results, examples of differentially expressed genes with significant differences between vaccinated and unvaccinated fish (t-test, n = 6 and 5, p < 0.05). Results for unvaccinated fish are not shown, data are log2-ER ± SE.Back to article page