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Table 1 List of the genes up-regulated by enteric glial cells in intestinal epithelial cells.

From: Regulation of intestinal epithelial cells transcriptome by enteric glial cells: impact on intestinal epithelial barrier functions

Gene Symbol Genbank Description % up-regulation (/control) Fold difference
TXNIP NM_006472 thioredoxin interacting protein 217,60 3,18
ANKRD1 NM_014391 ankyrin repeat domain 1 (cardiac muscle) 169,22 2,69
FN1 U42593 fibronectin 1 152,16 2,52
TUBB3 NM_006086 tubulin, beta 3 149,94 2,50
MGLL AJ270950 monoglyceride lipase 135,97 2,36
METTL7A NM_014033 methyltransferase like 7A 132,96 2,33
PKN2 NM_006256 protein kinase N2 128,33 2,28
/ XM_166201 synonyms: KIAA0056, MGC104671; Homo sapiens KIAA0056 protein (hCAP-D3), mRNA. 115,09 2,15
EPB41L2 NM_001431 erythrocyte membrane protein band 4.1-like 2 110,50 2,11
AASS AJ007714 aminoadipate-semialdehyde synthase 110,15 2,10
ACTG2 NM_001615 actin, gamma 2, smooth muscle, enteric 102,56 2,03
B4GALT5 NM_004776 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 102,38 2,02
SNX2 NM_003100 sorting nexin 2 102,38 2,02
VIP NM_003381 vasoactive intestinal peptide 102,33 2,02
EIF4A2 NM_001967 eukaryotic translation initiation factor 4A, isoform 2 102,14 2,02
/ NM_019027 RNA-binding protein 101,66 2,02
POLR3F NM_006466 polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa 94,46 1,94
PNRC1 NM_006813 proline-rich nuclear receptor coactivator 1 93,24 1,93
NPPB NM_002521 natriuretic peptide precursor B 83,97 1,84
/ BC017857 Homo sapiens cDNA clone IMAGE:4690793, with apparent retained intron. 82,20 1,82
KRT8 NM_002273 keratin 8 81,96 1,82
SAT1 NM_002970 spermidine/spermine N1-acetyltransferase 1 80,24 1,80
ASS1 NM_000050 argininosuccinate synthetase 1 76,73 1,77
S100A11P NM_021039 / 75,22 1,75
SLC7A7 NM_003982 solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 72,31 1,72
HAGH NM_005326 hydroxyacylglutathione hydrolase 69,54 1,70
BNIP3L AF536326 BCL2/adenovirus E1B 19 kDa interacting protein 3-like 69,19 1,69
/ AF195968 PRR5-ARHGAP8 fusion 68,01 1,68
BNIP3 NM_004052 BCL2/adenovirus E1B 19 kDa interacting protein 3 67,84 1,68
IL18 NM_001562 interleukin 18 (interferon-gamma-inducing factor) 67,14 1,67
RDM1 BC038301 RAD52 motif 1 67,11 1,67
FAM107B NM_031453 family with sequence similarity 107, member B 65,70 1,66
PLAC8 NM_016619 placenta-specific 8 63,77 1,64
SMARCA1 NM_139035 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 63,72 1,64
PLOD2 NM_000935 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 62,87 1,63
TMSB4Y NM_004202 thymosin, beta 4, Y-linked 62,77 1,63
SCPEP1 NM_021626 serine carboxypeptidase 1 60,96 1,61
LAMA5 NM_005560 laminin, alpha 5 60,53 1,61
LAMC1 NM_002293 laminin, gamma 1 (formerly LAMB2) 59,89 1,60
METAP1 BC030054 methionyl aminopeptidase 1 59,55 1,60
IQGAP2 NM_006633 IQ motif containing GTPase activating protein 2 58,98 1,59
C1orf43 NM_015449 chromosome 1 open reading frame 43 56,86 1,57
CASP4 NM_001225 caspase 4, apoptosis-related cysteine peptidase 55,71 1,56
BTG1 NM_001731 B-cell translocation gene 1, anti-proliferative 54,63 1,55
SLC2A1 K03195 solute carrier family 2 (facilitated glucose transporter), member 1 54,34 1,54
DCTN2 NM_006400 dynactin 2 (p50) 52,68 1,53
TOP2A NM_001067 topoisomerase (DNA) II alpha 170 kDa 52,42 1,52
KRT18 NM_000224 keratin 18 51,16 1,51
LAMC1 M55210 laminin, gamma 1 (formerly LAMB2) 50,37 1,50
PRC1 BC005140 protein regulator of cytokinesis 1 50,13 1,50
IMPDH2 NM_000884 IMP (inosine monophosphate) dehydrogenase 2 49,46 1,49
/ AF202922 LRP16 protein 48,20 1,48
PLD3 NM_012268 phospholipase D family, member 3 46,99 1,47
RNF4 NM_002938 ring finger protein 4 44,88 1,45
/ AC060225 Homo sapiens 3 BAC RP11-23J16 complete sequence. 42,10 1,42
SMARCA1 NM_003069 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 41,18 1,41
DYNLT3 NM_006520 dynein, light chain, Tctex-type 3 40,06 1,40
PPARG NM_015869 peroxisome proliferative activated receptor, gamma 38,92 1,39
GLRX AF069668 glutaredoxin (thioltransferase) 37,78 1,38
PTK2 NM_153831;NM_005607 PTK2 protein tyrosine kinase 2 37,72 1,38
CDH1 NM_004360 cadherin 1, type 1, E-cadherin (epithelial) 36,87 1,37
RNASE4 NM_002937 ribonuclease, RNase A family, 4 31,40 1,31
CTSH NM_004390 cathepsin H 29,45 1,29
MKI67 NM_002417 antigen identified by monoclonal antibody Ki-67 29,28 1,29
EIF2A NM_032025 eukaryotic translation initiation factor 2A, 65 kDa 26,54 1,27
TGFBI BC000097 transforming growth factor, beta-induced, 68 kDa 25,95 1,26
MLLT3 NM_004529 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 22,42 1,22
APOBEC3B NM_004900 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 22,20 1,22
ADD3 NM_019903 adducin 3 (gamma) 20,82 1,21
FTH1 NM_002032 ferritin, heavy polypeptide 1 15,97 1,16