Skip to main content


Table 5 Lists of differentially expressed genes involved in signalling pathways regulated in intestinal epithelial cells by enteric glial cells.

From: Regulation of intestinal epithelial cells transcriptome by enteric glial cells: impact on intestinal epithelial barrier functions

Ingenuity© Signalling Pathway Genes Ratio
Circadian Rhythm Signaling VIP 0.046
Cell Cycle: G1/S Checkpoint Regulation SMAD3, E2F1 0.041
Integrin Signaling ACTG2, FN1, LAMA5, LAMC1, PTK2 0.03
Actin Cytoskeleton Signaling TMSB4Y, FGFR2, FN1, ITGAE, IQGAP2, PTK2 0.029
Cell Cycle: G2/M DNA Damage Checkpoint Regulation TOP2A 0.029
VEGF Signaling ACTG2, PTK2 0.029
Complement and Coagulation Cascades FGG, C6 0.028
Amyloid Processing CDK5R1 0.028
ERK/MAPK Signaling PRKCD, PPARG, PTK2 0.024
Wnt/β-catenin Signaling CDH1, MARK2, SFRP4 0.022
FGF Signaling FGFR2 0.018
Chemokine Signaling PTK2 0.018
TGF-β Signaling SMAD3 0.016
Protein Ubiquitination Pathway PSMC6, PSMC1, BAG1 0.016
PPAR Signaling PPARG 0.015
IGF-1 Signaling PTK2 0.015
Apoptosis Signaling PRKCQ 0.015
Neuregulin Signaling CDK5R1 0.015
PTEN Signaling PTK2 0.014
Fc Epsilon RI Signaling PRKCD 0.014
T Cell Receptor Signaling PRKCQ 0.014
Xenobiotic Metabolism Signaling PRKCD, PRKCQ 0.010
NF-κB Signaling PRKCQ 0.009
B Cell Receptor Signaling PRKCQ 0.009
Ephrin Receptor Signaling PTK2 0.009
Leukocyte Extravasation Signaling PTK2 0.008
Huntington's Disease Signaling CDK5R1 0.007
Axonal Guidance Signaling PTK2 0.004