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Table 1 Putative CNVs called on 100 K and 500 K AGH in 54 trios tested with both technologies.

From: Detection of pathogenic copy number variants in children with idiopathic intellectual disability using 500 K SNP array genomic hybridization

 

Comparison

Child to Father

Child to Mother

 

Array

100 K

500 K

100 K

500 K

All CNV Calls

Number

125

497

110

501

 

Number per Child

2.31

9.20

2.04

9.28

 

Statistical Significance

t = 7.18, p < 0.0001

t = 6.67, p < 0.0001

CNV Calls < 100 kb

Number

59

237

53

221

 

Number per Child

1.06

4.39

0.98

4.09

 

Statistical Significance

t = 7.82, p < 0.0001

t = 5.19, p < 0.0001

CNV Calls ≥ 100 kb and < 200 kb

Number

13

130

12

146

 

Number per Child

0.24

2.41

0.22

2.70

 

Statistical Significance

t = 5.39, p < 0.0001

t = 6.27, p < 0.0001

CNV Calls ≥ 200 kb and < 500 kb

Number

33

101

25

98

 

Number per Child

0.61

1.87

0.46

1.81

 

Statistical Significance

t = 4.66, p < 0.0001

t = 5.25, p < 0.0001

  1. Two-tailed statistical significance was calculated with Student's t-test.
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BMC Genomics

ISSN: 1471-2164

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