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Table 2 MIPS functional categories specifically associated with combinatorial effects

From: Combinatorial effects of environmental parameters on transcriptional regulation in Saccharomyces cerevisiae: A quantitative analysis of a compendium of chemostat-based transcriptome data

  Enrichment p-values
MIPS category single effects comb. effect
  Acetate Ethanol both Acetate | Ethanol
METABOLISM 0.065 0.077 1 7.8·10-18
metabolism of glutamate 1 0.048 1 1.4·10-6
C-compound and carbohydrate metabolism 0.027 0.082 1 1.4·10-22
C-compound and carbohydrate utilization 0.02 0.043 1 1.3·10-17
C-compound, carbohydrate catabolism 0.2 1 1 8·10-13
sugar, glucoside, polyol and carboxylate catabolism 0.44 1 1 9.3·10-11
ENERGY 0.013 1 1 1·10-17
glycolysis and gluconeogenesis 1 1 1 3.8·10-9
tricarboxylic-acid pathway 1 1 1 2.2·10-11
  Phosphorus Sulfur both Phosphorus | Sulfur
transcriptional control 0.13 0.017 1 4.3·10-8
RNA processing 0.86 0.32 1 1.5·10-6
rRNA processing 0.5 0.83 1 3.3·10-6
  1. The combinatorial effects 'carbon source acetate OR ethanol' and 'Limiting element phosphorus OR sulfur' are specifically associated to the listed MIPS functional categories. P-values of the enrichment of genes within these categories that are affected by the combinatorial effect are given in the rightmost column. Also, enrichment p-values of genes affected by each and by both of the single effects that constitute this combinatorial effect are given.
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BMC Genomics

ISSN: 1471-2164

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