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Table 2 MIPS functional categories specifically associated with combinatorial effects

From: Combinatorial effects of environmental parameters on transcriptional regulation in Saccharomyces cerevisiae: A quantitative analysis of a compendium of chemostat-based transcriptome data

 

Enrichment p-values

MIPS category

single effects

comb. effect

 

Acetate

Ethanol

both

Acetate | Ethanol

METABOLISM

0.065

0.077

1

7.8·10-18

metabolism of glutamate

1

0.048

1

1.4·10-6

C-compound and carbohydrate metabolism

0.027

0.082

1

1.4·10-22

C-compound and carbohydrate utilization

0.02

0.043

1

1.3·10-17

C-compound, carbohydrate catabolism

0.2

1

1

8·10-13

sugar, glucoside, polyol and carboxylate catabolism

0.44

1

1

9.3·10-11

ENERGY

0.013

1

1

1·10-17

glycolysis and gluconeogenesis

1

1

1

3.8·10-9

tricarboxylic-acid pathway

1

1

1

2.2·10-11

 

Phosphorus

Sulfur

both

Phosphorus | Sulfur

transcriptional control

0.13

0.017

1

4.3·10-8

RNA processing

0.86

0.32

1

1.5·10-6

rRNA processing

0.5

0.83

1

3.3·10-6

  1. The combinatorial effects 'carbon source acetate OR ethanol' and 'Limiting element phosphorus OR sulfur' are specifically associated to the listed MIPS functional categories. P-values of the enrichment of genes within these categories that are affected by the combinatorial effect are given in the rightmost column. Also, enrichment p-values of genes affected by each and by both of the single effects that constitute this combinatorial effect are given.