Figure 2
From: Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells
Expression profiles of genes correlated to four transcription factors. A hierarchical clustering was applied to the HRG-induced gene expression profiles of those genes correlated with the selected transcription factors (EGR4, FOSL-1, FHL2 and DIPA) and the results are shown as a heat map. If multiple probe sets with the same Gene ID were selected for the same transcription factor, a probe set which showed maximum I was selected in this analysis. Correlated transcription factors are highlighted in black in the right panel of the figure. Expression levels were normalized to yield mean and standard deviation values of 0 and 1, respectively, before applying the clustering algorithm. High and low expression levels are depicted in red and blue, respectively.