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Table 1 Overview of the differences between the original RefSeq annotation and the reannotation

From: Genome reannotation of Escherichia coli CFT073 with new insights into virulence

  Original annotation
(RefSeq: NC_004431)
Reannotation
Genome length 5,231,426 bp
plasmids None
G+C% 50.47%
Protein-coding genes 5,339 5,030
tRNAs 89
rRNAs 21
Miscellaneous RNAsa 6 46
Backbone genesb 4,550 (4,440 protein-coding genes, 85 tRNA genes, 21 rRNA genes, and 4 miscellaneous RNA genes) 4,328 (4,178 protein-coding genes, 85 tRNA genes, 21 rRNA genes, and 44 miscellaneous RNA genes)
Genomic island genesc 905 (899 protein-coding genes, 4 tRNA genes, and 2 miscellaneous RNA genes) 851 (845 protein-coding genes, 4 tRNA genes, and 2 miscellaneous RNA genes)
Cryptic prophages 5
  1. aThe concept of miscellaneous RNA here includes tRNAs, rRNAs and all other RNAs;
  2. bIn this comparison, we define the genes other than those in the genomic island regions as backbone genes;
  3. cThe genes located in genomic island regions (data conducted by Lloyd and et al [47]).