Analysis of recent segmental duplications in the bovine genome

BMC Genomics

Table 2 Repertoires and evolutionary mechanisms of selected duplicated genes or gene families in mammals

	Bovine	Human	Mouse	Dog	Mechanisms
Cytochrome P-450	~65	57	102	54	Duplication, inactivation; positive selection [43]
Ribonuclease A	21	13	25	7	Duplication, deletion, inactivation; positive selection and alternative splicing [39]
β-Defensins	~106	39	52	43	Duplication, deletion, inactivation; positive selection [29, 41, 42]
IFNA	13	13	14	9	Duplication, deletion, inactivation; no strong positive selection but strong gene conversion [44, 45]
Olfactory Receptor	1152	388	1063	822	Duplication, deletion, inactivation; positive selection [40]
TCRV*	170	111	78	41	Duplication, deletion, inactivation; positive selection [46]
C-type Lysozyme	10	1	3	2	Duplication; positive selection [29]

As many of these duplicated genes are present in unassigned chromosomes, gene numbers in the bovine genome are based on the cited literature and some of them are just best estimates. *Based on searches on the international ImMunoGeneTics (IMGT) information system at http://www.imgt.org/.

ISSN: 1471-2164