Figure 2

Top-Scoring Classifiers and Distributions of Classifier Accuracies. A: The distribution of all possible gene pair classifiers according to accuracy in the diagnosis of GIST and LMS, for both original data and randomly permuted data with randomized class labels. Vertical axis represents the fraction of pairs achieving the indicated accuracy. B: Plot comparing the expression level of the two genes from the top-scoring classifier as measured through a microarray platform, with a line of slope one and intercept of zero separating the two phenotypes according to the more highly expressed transcript. (Figure adapted from data originally published in [26].) C and D: Classifier accuracy distribution and top-scoring classifier microarray gene expression values for the diagnosis Crohns's Disease from circulating leukocytes. E and F: Accuracy distribution and top-scoring classifier in the diagnosis of ischemic and idiopathic cardiomyopathy.