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Figure 15 | BMC Genomics

Figure 15

From: The pitfalls of platform comparison: DNA copy number array technologies assessed

Figure 15

For a pool-pool hybridization from the Agilent platform depicted are the distribution and effect of probe target length. Top left: depicted are numbers of probes apparently targeting sequences of different lengths, with modes at 60 and 45. Bottom left: Shown are the proportions of probes, for each autosomal chromosome, that have target length 60; a proportion that is lowest for chromosome 19. Note that the width of the bar is proportional to the total number of probes on that array. Right: Two boxplots depict the associations between probe target length and intensity, and probe target length and log-ratio. 60 mer target sequence lengths are associated with lower intensities and greater variance of log-ratio.

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