Figure 5

Relationship between the number of miRNA binding sites and mRNA decay rate. (a) Variation of mRNA decay rates for 5 miRNA binding site groups with increasing number of binding sites. The degree of the increasing trend for mRNA decay rates along with the increasing number of miRNA binding sites was estimated by Wilcoxon rank sum tests and depicted in p-values. (b) The expected variation of mRNA decay rates from both permutation tests and shuffled 3'UTR sequences for 5 miRNA binding site groups with increasing number of binding sites. (c) Variation of miRNA binding site number for 5 mRNA decay rate groups with increasing decay rates. The degree of the increasing trend for miRNA binding site number along with the increasing mRNA decay rates was estimated by Wilcoxon rank sum tests and depicted in p-values. (d) The expected variation of miRNA binding site number from both permutation tests and shuffled 3'UTR sequences for 5 mRNA decay rate groups with increasing decay rates.