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Table 1 TFs that are predicted to have a central role in regulating miRNAs

From: Deciphering the transcriptional circuitry of microRNA genes expressed during human monocytic differentiation

Gene Symbol

Gene ID

Hits in subset

Number of associations in subset

Total number of hits

Total number of associations

p-Value

p-Value (Bonferroni corrected)

CREB1

1385

18

 

20

 

1.33E-09

3.43E-07

ATF2

1386

15

 

17

 

6.56E-08

1.69E-05

SP3

6670

13

 

14

 

1.46E-07

3.76E-05

NFE2L2

4780

12

 

13

 

5.52E-07

1.42E-04

NFE2L1

4779

10

 

10

 

9.04E-07

2.33E-04

YY1

7528

10

498

11

1,989

7.72E-06

1.99E-03

CEBPB

1051

10

 

11

 

7.72E-06

1.99E-03

RUNX1

861

11

 

13

 

1.04E-05

2.69E-03

USF2

7392

9

 

10

 

2.85E-05

7.35E-03

E2F3

1871

13

 

18

 

3.18E-05

8.21E-03

ELK1

2002

10

 

12

 

3.59E-05

9.27E-03

HOXA4

3201

11

 

14

 

3.77E-05

9.74E-03

  1. Table 1 shows the TFs that have been identified through statistical analysis to be statistically enriched (corrected p-value < 0.01) within the upper quartile of predicted TF→miRNA associations (see text). The correction factor utilised for the Bonferroni-correction is the number of unique TFs in the complete set of predicted TF→miRNA associations (258).
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BMC Genomics

ISSN: 1471-2164

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