The transcriptional programme of Salmonella enterica serovar Typhimurium reveals a key role for tryptophan metabolism in biofilms

Table 2 Biofilm-regulated proteins that show similar trends in proteomic and transcriptomic analysis.

Protein^a	Function	Average fold expression in the biofilm compared to planktonic (n = 2)
DppA	ABC superfamily dipeptide transport protein	+ 10.7
TreA	Periplasmic trehalase	Unique to biofilm
GalE	UDP-galactose-4-epimerase	+ 2.9
YggE	Putative periplasmic immunogenic protein	+ 3.7
YciF	Putative cytoplasmic protein	Unique to biofilm
YajQ	Putative cytoplasmic protein	Unique to biofilm
FlgL	Flagella hook-filament junction protein (HAP3)	+ 44.0
IadA	Putative isoaspartyl dipeptidase	Unique to planktonic
FliD	Flagellar filament cap protein (HAP2)	Unique to biofilm
FlgK	Flagellar hook-filament junction protein (HAP1)	+ 3.3
AnsB	Periplasmic L-asparaginase II protein	+ 2.9
ArgT	ABC superfamily; lysine/arginine/orthinine tranport protein	+ 4.9

a. Proteins identified by MALDI-TOF mass spectrometry and peptide mass fingerprinting (Mascot). Proteins up-regulated in the biofilm that show the same pattern of expression at the transcriptional level (Additional files 2 and 3).

ISSN: 1471-2164