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Table 3 The effect of repeat unit sequence on microsatellite heterozygosity for tetra-nucleotide loci

From: Sequence determinants of human microsatellite variability

  AAAT & TTTA AATG CATA & GTAT TTCA GATG ATCT & TAGA AAGG & TTCC
Number of loci 30 4 8 3 5 253 18
Mean H e 0.683 0.691 0.714 0.719 0.722 0.744 0.789
AAAT [AATA-ATAA-TAAA] & TTTA [TTAT-TATT-ATTT]   0.979 0.407 0.416 0.421 4.49 × 10 -4 4.80 × 10 -5
AATG [ATGA-TGAA-GAAT]    0.808 0.857 0.556 0.229 0.066
CATA [ATAC-TACA-ACAT] & GTAT [TATG-ATGT-TGTA]     0.921 1 0.239 0.011
TTCA [TCAT-CATT-ATTC]      0.786 0.541 0.080
GATG [ATGG-TGGA-GGAT]       0.304 0.019
ATCT [TCTA-CTAT-TATC] & TAGA [AGAT-GATA-ATAG]        0.003
AAGG [AGGA-GGAA-GAAG] & TTCC [TCCT-CCTT-CTTC]        
  1. P values are shown for two-sided Wilcoxon rank-sum tests for differences in heterozygosity (H e ) between the different repeat unit sequences of microsatellites with one tetra-nucleotide STR region. Four loci were excluded from these comparisons because their repeat unit sequences only appeared once (TTTG and GAAA) or twice (TCCA) in the data set. Tests with P < 0.05 are highlighted in bold.