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Table 4 The effect of the number of separate STR regions on microsatellite heterozygosity

From: Sequence determinants of human microsatellite variability

 

Di

Tri

Tetra

 

1 STR

2 STRs

1 STR

2 STRs

1 STR

2 STRs

3 STRs

Number of loci

30

10

133

15

325

97

12

Mean H e

0.779

0.789

0.749

0.721

0.739

0.772

0.814

1 STR region

0.770

  

0.319

 

3.12 × 10 -5

4.23 × 10 -4

STR regions

      

0.049

  1. P values are shown for two-sided Wilcoxon rank-sum tests for differences in heterozygosity (H e ) between microsatellites with one, two, or three separate STR regions. Loci are grouped by their repeat unit size. For di-nucleotide and tri-nucleotide loci, because of small sample size (3 and 2, respectively), the column for three separate STR regions was omitted. Tests with P < 0.05 are highlighted in bold.
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BMC Genomics

ISSN: 1471-2164

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