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Table 4 The effect of the number of separate STR regions on microsatellite heterozygosity

From: Sequence determinants of human microsatellite variability

  Di Tri Tetra
  1 STR 2 STRs 1 STR 2 STRs 1 STR 2 STRs 3 STRs
Number of loci 30 10 133 15 325 97 12
Mean H e 0.779 0.789 0.749 0.721 0.739 0.772 0.814
1 STR region 0.770    0.319   3.12 × 10 -5 4.23 × 10 -4
STR regions        0.049
  1. P values are shown for two-sided Wilcoxon rank-sum tests for differences in heterozygosity (H e ) between microsatellites with one, two, or three separate STR regions. Loci are grouped by their repeat unit size. For di-nucleotide and tri-nucleotide loci, because of small sample size (3 and 2, respectively), the column for three separate STR regions was omitted. Tests with P < 0.05 are highlighted in bold.