Skip to main content

Advertisement

Table 6 Spearman's rank correlations of heterozygosity with skewness in the number of repeats across individuals

From: Sequence determinants of human microsatellite variability

  1 STR region 2 STR regions 3 STR regions
  Di Tri Tetra Di Tri Tetra Tetra
Number of loci 12 73 201 7 12 55 4
γ1 < 0 -0.105 -0.333 -0.291 -0.286 -0.252 -0.124 -
Number of loci 18 60 124 3 3 42 8
γ1 > 0 -0.007 -0.545 -0.043 - - -0.225 -0.143
  1. Spearman's rank correlation coefficients (ρ) are shown for comparisons of microsatellite heterozygosity with skewness in the distribution of the number of repeats across individuals in the HGDP-CEPH data set. Microsatellites were classified by the number of separate STR regions embedded in their sequence, by their repeat unit size, and based on whether skewness (γ1) was greater or less than zero. Hyphens indicate comparisons that were not evaluated. For three STR regions, no comparisons were performed for di-nucleotide and tri-nucleotide loci because of small sample size (3 and 2, respectively). Correlations with P < 0.05 are highlighted in bold.