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Table 6 Enrichment of Molecular Functions of Genes containing AARs

From: The expansion of amino-acid repeats is not associated to adaptive evolution in mammalian genes

GO.ID Term1 Corrected p-value2
GO:0050825 ice binding < 1E-26
GO:0003677 DNA binding 4.01E-15
GO:0003700 transcription factor activity 1.26E-13
GO:0043565 sequence-specific DNA binding 5.79E-13
GO:0005199 structural constituent of cell wall 1.00E-08
GO:0004879 ligand-dependent nuclear receptor activity 3.15E-07
GO:0003682 chromatin binding 2.54E-06
GO:0003723 RNA binding 7.63E-05
GO:0008270 zinc ion binding 0.000303826
GO:0004969 histamine receptor activity 0.0008013
GO:0045735 nutrient reservoir activity 0.0008013
GO:0003702 RNA polymerase II transcription factor activity 0.001116964
GO:0003676 nucleic acid binding 0.001580342
GO:0003705 RNA polymerase II transcription factor activity, enhancer binding 0.009862154
GO:0003735 structural constituent of ribosome 0.02671
GO:0005249 voltage-gated potassium channel activity 0.049858667
GO:0004386 helicase activity 0.065105625
GO:0016563 transcription activator activity 0.13355
GO:0003714 transcription corepressor activity 0.13355
GO:0005179 hormone activity 0.199622105
  1. 1 In bold terms overrepresented also for genes hosting the highest average purity of their AARs; 2 FDR < 20%.