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Table 6 Enrichment of Molecular Functions of Genes containing AARs

From: The expansion of amino-acid repeats is not associated to adaptive evolution in mammalian genes

GO.ID

Term1

Corrected p-value2

GO:0050825

ice binding

< 1E-26

GO:0003677

DNA binding

4.01E-15

GO:0003700

transcription factor activity

1.26E-13

GO:0043565

sequence-specific DNA binding

5.79E-13

GO:0005199

structural constituent of cell wall

1.00E-08

GO:0004879

ligand-dependent nuclear receptor activity

3.15E-07

GO:0003682

chromatin binding

2.54E-06

GO:0003723

RNA binding

7.63E-05

GO:0008270

zinc ion binding

0.000303826

GO:0004969

histamine receptor activity

0.0008013

GO:0045735

nutrient reservoir activity

0.0008013

GO:0003702

RNA polymerase II transcription factor activity

0.001116964

GO:0003676

nucleic acid binding

0.001580342

GO:0003705

RNA polymerase II transcription factor activity, enhancer binding

0.009862154

GO:0003735

structural constituent of ribosome

0.02671

GO:0005249

voltage-gated potassium channel activity

0.049858667

GO:0004386

helicase activity

0.065105625

GO:0016563

transcription activator activity

0.13355

GO:0003714

transcription corepressor activity

0.13355

GO:0005179

hormone activity

0.199622105

  1. 1 In bold terms overrepresented also for genes hosting the highest average purity of their AARs; 2 FDR < 20%.