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Figure 4 | BMC Genomics

Figure 4

From: Revisiting the missing protein-coding gene catalog of the domestic dog

Figure 4

D N / d S distributions of benchmark and test sets. A. The dN/dS distribution (as log dN/dS) of the test set (new predicted genes) is represented in purple and benchmark set (human-dog 1:1 orthologous) is represented in blue. Test set exhibits a dN/dS distribution similar to the benchmark set (Mann-Whitney; P = 0.16) suggesting comparable selective constraints for both sets. B. In contrast the dN/dS distribution of the pseudogene (with accumulated mutations) set (red) is significantly shifted upwards (Mann-Whitney; P = 5.17e - 6) in comparison to the benchmark set, indicating relaxation of selective constraints on the predicted pseudogenes.

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