Table 2 Differential expression pattern at pH 6 in comparison to pH 7.5
Genes induced at pH 6 | Transcriptome4 | Proteome5 | Regulators6 | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cytoplasm | envelope | membrane | |||||||||||||||
No | gene ID1 | op2 | gene | function | TMH3 | pH 6 | pH 9 | 6 | 7.5 | 9 | 6 | 7.5 | 9 | 6 | 7.5 | 9 | |
1 | cg0012 | Hypothetical protein | 0 | 1.45 | n.d. | - | - | - | 2.5 | - | - | - | - | - | McbR* | ||
2 | cg0325 | Multisubunit Na+/H+ antiporter | 2 | 1.04 | 0.17 | - | - | - | 0.6 | 1.3 | 0.8 | - | - | - | |||
3 | cg0360 | Putative phosphatase | 1 | 1.35 | n.d. | - | - | - | - | - | - | - | - | - | |||
4 | cg0403 | b | rmlB1 | dTDP-glucose 4,6-dehydratase | 0 | 1.04 | n.d. | - | - | - | - | - | - | - | - | - | |
5 | cg0404 | b | Nitroreductase family | 0 | 1.77 | -1.50 | 3.4 | 2.5 | 0.9 | 0.9 | - | - | -0.9 | - | - | ||
6 | cg0550 | Putative peptidase E | 0 | 1.10 | -0.46 | - | - | - | - | - | - | - | - | - | |||
7 | cg0736 | k | metN | ATPase component | 0 | 1.45 | n.d. | 2.2 | - | - | 5.1 | 2.8 | 2.6 | 4.0 | 1.7 | -0.6 | McbR*, RamB* |
8 | cg0737 | k | metQ | periplasmic component | 0 | 1.85 | -0.69 | 5.4 | 3.4 | 3.5 | 7.2 | 4.1 | 4.7 | 9.1 | 6.8 | 6.7 | McbR*, RamB* |
9 | cg0754 | l | metX | Homoserine O-acetyltransferase | 0 | 1.19 | n.d. | 2.1 | - | -0.8 | 2.5 | - | -0.3 | - | - | - | McbR* |
10 | cg0755 | l | metY | O-acetylhomoserine sulfhydrylase | 0 | 2.43 | -0.08 | 6.6 | 4.8 | 5.4 | 3.3 | 0.7 | 1.4 | 1.7 | - | - | McbR* |
11 | cg0874 | Uncharacterized ACR, COG2135 | 0 | 1.03 | 0.46 | - | - | - | -0.4 | - | - | - | - | - | |||
12 | cg0878 | whiB1 | Stress response transcription factor WhiB1 | 0 | 1.26 | 0.49 | - | - | - | - | - | - | - | - | - | SigH, GlxR* | |
13 | cg1081 | p | ABC-type multidrug transport system, ATPase component | 0 | 1.18 | 0.86 | -0.3 | -0.8 | 0.0 | 2.0 | 2.6 | 3.3 | 3.0 | 3.3 | 4.4 | ||
14 | cg1082 | p | ABC-type multidrug transporter, permease components | 6 | 1.33 | 0.68 | - | - | - | - | - | 1.4 | - | - | - | ||
15 | cg1083 | p | cgtS10 | Two-component system, sensory transduction histidine kinases | 5 | 1.38 | 0.64 | - | - | - | - | - | 1.0 | - | - | - | SigB* |
16 | cg1129 | aroG | Phospho-2-dehydro-3-deoxyheptonate aldolase | 0 | 1.44 | n.d. | 1.1 | 1.5 | - | 2.4 | 2.6 | - | -0.7 | 1.4 | - | ||
17 | cg1150 | NADPH dependent FMN reductase | 0 | 1.02 | n.d. | 1.2 | - | - | - | - | - | - | - | - | |||
18 | cg1202 | Hypothetical protein | 0 | 1.23 | n.d. | - | - | - | - | - | - | - | - | - | |||
19 | cg1214 | q | sufS | Cysteine desulfurase involved in maturation of Fe-S clusters | 0 | 1.30 | -0.37 | -0.6 | - | - | 1.4 | -0.3 | - | - | - | - | NrtR* |
20 | cg1215 | q | nadC | Nicotinate-nucleotide pyrophosphorylase | 0 | 1.30 | -0.06 | 5.1 | 4.2 | 3.6 | 1.2 | - | - | 2.1 | - | 1.6 | NrtR* |
21 | cg1216 | q | nadA | Quinolinate synthetase A | 0 | 1.77 | -0.20 | - | 0.2 | 0.7 | 2.2 | 2.6 | - | - | 0.7 | - | NrtR* |
22 | cg1218 | q | nrtR | Regulator NrtR, ADP-ribose pyrophosphatase | 0 | 1.58 | -0.24 | - | - | - | - | - | - | - | - | - | NrtR* |
23 | cg1256 | dapD | Tetrahydrodipicolinate N-succinyltransferase | 0 | 1.25 | n.d. | 2.5 | 0.4 | - | 5.0 | 3.6 | 2.4 | -0.9 | - | - | ||
24 | cg1291 | Hypothetical membrane protein | 2 | 2.43 | n.d. | - | - | - | 0.9 | - | - | - | - | - | |||
25 | cg1322 | Uncharacterized beta barrel protein | 0 | 1.24 | -0.62 | 6.3 | 5.1 | 2.7 | - | - | - | 2.6 | -0.6 | - | |||
26 | cg1337 | hom | Homoserine dehydrogenase | 0 | 1.68 | 0.22 | 4.4 | 2.4 | 3.0 | 5.4 | 4.5 | 4.0 | 3.1 | 3.2 | 1.4 | McbR | |
27 | cg1344 | s | narG | Nitrate reductase | 0 | 1.36 | 1.94 | - | - | -0.6 | - | - | - | - | - | -0.4 | RipA, GlxR* |
28 | cg1476 | thiC | Thiamine biosynthesis protein | 0 | 1.00 | 0.62 | 3.9 | 3.8 | 4.1 | 2.9 | 2.3 | 3.6 | 1.8 | 1.4 | 1.0 | ||
29 | cg1478 | Hypothetical protein | 0 | 4.89 | n.d. | -0.6 | - | - | - | - | - | - | - | - | LexA | ||
30 | cg1580 | v | argC | N-acetyl-gamma-glutamyl-phosphate reductase | 0 | 1.65 | -0.17 | 2.9 | 2.2 | 2.2 | 1.3 | -0.2 | - | -0.9 | - | - | ArgR |
31 | cg1581 | v | argJ | Glutamate N-acetyltransferase | 0 | 2.03 | -0.02 | 5.8 | 5.0 | 5.2 | 2.8 | 2.1 | 2.1 | - | - | - | ArgR |
32 | cg1582 | v | argB | Acetylglutamate kinase | 0 | 1.84 | n.d. | 1.1 | - | -0.8 | 3.1 | - | 0.0 | - | - | - | ArgR |
33 | cg1583 | v | argD | Acetylornithine aminotransferase | 0 | 1.66 | n.d. | 1.9 | 0.9 | 0.2 | - | - | - | - | - | - | ArgR |
34 | cg1584 | v | argF | Ornithine carbamoyltransferase | 0 | 1.75 | -0.12 | 1.2 | 0.4 | -0.2 | - | - | - | - | - | - | ArgR |
35 | cg1586 | v | argG | Argininosuccinate synthase | 0 | 1.16 | 0.05 | 4.1 | 4.3 | 4.3 | 5.4 | 5.2 | 5.1 | 3.1 | 3.5 | 2.8 | |
36 | cg1626 | w | Hypothetical secreted protein | 0 | 2.12 | n.d. | - | - | - | - | - | - | - | - | - | ||
37 | cg1628 | w | Putative hydrolase | 0 | 2.25 | n.d. | - | - | - | 1.9 | - | - | - | - | - | ||
38 | cg1647 | ABC-type multidrug transporter, permease components | 5 | 1.06 | -0.01 | - | - | - | -0.4 | - | -0.3 | - | - | - | AmtR* | ||
39 | cg1701 | metH | Homocysteine Methyltransferase | 0 | 2.22 | 0.12 | 1.1 | - | - | 3.7 | 3.1 | 0.7 | - | - | -0.6 | McbR* | |
40 | cg1739 | GMP synthase-Glutamine amidotransferase domain | 0 | 1.36 | n.d. | - | - | - | - | - | - | - | - | - | McbR* | ||
41 | cg1806 | metK | S-adenosylmethionine synthetase | 0 | 1.29 | -0.17 | 2.9 | 2.3 | 1.1 | 3.6 | 2.9 | - | - | - | - | McbR | |
42 | cg1940 | Hypothetical protein | 1 | 1.18 | -0.08 | - | - | - | - | - | - | - | - | - | |||
43 | cg2051 | Hypothetical protein | 0 | 1.25 | n.d. | - | - | - | - | - | - | - | - | - | |||
44 | cg2157 | terC | putative tellurium exporter TerC | 9 | 1.05 | -0.13 | - | - | - | 2.8 | 2.4 | 1.5 | 1.5 | 1.0 | 2.3 | ||
45 | cg2250 | Hypothetical protein | 0 | 1.16 | n.d. | - | - | - | 0.6 | - | -0.3 | 1.6 | - | 1.1 | |||
46 | cg2260 | glnK | Nitrogen regulatory protein PII | 0 | 1.13 | n.d. | 1.2 | 2.2 | 1.4 | - | - | - | - | - | - | AmtR | |
47 | cg2338 | dnaE1 | DNA polymerase III, alpha chain | 0 | 1.12 | 0.29 | - | - | - | 0.0 | - | -0.3 | - | - | - | ||
48 | cg2380 | Hypothetical membrane protein | 2 | 1.00 | 0.12 | - | - | - | 1.7 | 1.3 | 0.8 | - | - | -0.6 | |||
49 | cg2462 | TetR-type transcription factor | 0 | 1.12 | n.d. | - | - | - | - | - | - | - | - | - | |||
50 | cg2472 | Predicted hydrolase or acyltransferase | 0 | 1.14 | 0.48 | - | - | - | - | - | - | - | - | - | |||
51 | cg2576 | DNA polymerase III delta subunit | 0 | 1.17 | n.d. | - | - | - | - | - | - | - | - | - | |||
52 | cg2590 | Putative xanthine/uracil permease | 12 | 1.87 | n.d. | - | - | - | - | - | - | 0.2 | - | -0.6 | |||
53 | cg2591 | dkgA | 2,5-diketo-D-gluconic acid reductase | 0 | 1.72 | n.d. | 3.2 | 0.9 | 2.0 | - | - | - | - | - | - | ||
54 | cg2674 | ae | Putative Carboxymuconolactone decarboxylase | 0 | 1.08 | -0.25 | 3.0 | 2.8 | 2.5 | 1.5 | - | - | -0.9 | - | - | McbR* | |
55 | cg2675 | ae | ABC-type putative peptide transporter, duplicated ATPase component | 0 | 1.70 | n.d. | 0.8 | -0.4 | - | 3.9 | 0.8 | - | 0.2 | - | - | McbR* | |
56 | cg2677 | ae | ABC-type putative peptide transporter, permease subunit | 6 | 2.00 | n.d. | - | - | - | 3.9 | 0.8 | 1.9 | 2.9 | 1.6 | 1.5 | McbR* | |
57 | cg2678 | ae | ABC-type putative peptide transporter, periplasmic subunit | 0 | 1.90 | n.d. | 1.2 | - | -0.2 | 4.9 | 1.3 | 3.4 | 6.0 | 3.3 | 2.7 | McbR* | |
58 | cg2687 | metB | Cystathionine beta-lyases/cysta-thionine gamma-synthases | 0 | 1.34 | 0.37 | 5.3 | 4.2 | 5.1 | - | - | - | - | - | -0.4 | McbR* | |
59 | cg2748 | Hypothetical membrane protein | 2 | 1.21 | 0.86 | - | - | - | -0.4 | - | -0.3 | 2.7 | - | 1.8 | |||
60 | cg2761 | Metal-dependent hydrolases of the beta-lactamase superfamily III | 0 | 1.05 | -0.30 | 0.4 | -0.8 | - | - | - | - | - | - | - | |||
61 | cg2766 | MarA-type transcription factor | 0 | 1.20 | 0.69 | 0.7 | - | 1.5 | - | -0.3 | - | - | - | - | RamB* | ||
62 | cg2796 | af | prpD | Putative 2-methylcitrate dehydratase | 0 | 2.79 | n.d. | 4.7 | - | - | 2.0 | - | - | - | - | - | DtxR |
63 | cg2797 | af | Putative 2-phospho-3-sulpholactate synthase | 0 | 2.92 | n.d. | 2.4 | - | - | - | -0.2 | - | - | - | - | DtxR | |
64 | cg2834 | cysE | Serine O-Acetyltransferase | 0 | 1.48 | n.d. | - | -0.5 | - | 3.4 | 1.3 | 2.1 | 0.4 | - | - | ||
65 | cg2835 | Predicted acetyltransferase | 0 | 1.52 | 0.56 | 2.5 | - | 1.9 | 0.8 | - | - | - | - | - | |||
66 | cg2890 | Putative amino acid processing enzyme | 0 | 2.18 | n.d. | - | - | - | - | - | - | - | - | - | |||
67 | cg2891 | poxB | Pyruvate:quinone oxidoreductase | 0 | 2.02 | -0.21 | 3.6 | 0.4 | 0.3 | 0.6 | - | 0.9 | -0.9 | - | - | SigB* | |
68 | cg3049 | fprA | putative ferredoxin NADP oxidoreductases | 0 | 1.26 | 0.24 | 3.3 | 3.1 | 3.6 | 3.3 | 3.8 | 3.0 | 0.2 | 2.4 | -0.6 | ||
69 | cg3082 | ag | ArsR-type transcription factor | 0 | 3.34 | n.d. | - | - | - | - | - | - | - | - | - | DtxR | |
70 | cg3083 | ag | Predicted Co/Zn/Cd cation transporter | 6 | 3.42 | n.d. | - | - | - | 1.2 | - | - | - | - | - | DtxR | |
71 | cg3084 | ag | putative FAD dependent NAD(P)H disulphide oxidoreductase | 0 | 3.14 | n.d. | - | - | - | 2.6 | - | - | - | - | - | DtxR | |
72 | cg3085 | ag | putative FAD dependent oxidoreductase | 0 | 1.47 | n.d. | -0.6 | - | - | - | - | - | - | - | - | DtxR | |
73 | cg3112 | ah | cysZ | Sulfate permease | 7 | 4.03 | 0.32 | - | - | - | 3.8 | 0.8 | 2.6 | 2.6 | 0.7 | 1.6 | DtxR, McbR*, CysR* |
74 | cg3113 | ah | Putative metal chelatase | 0 | 3.31 | n.d. | - | - | - | - | - | - | - | - | - | DtxR, McbR*, CysR* | |
75 | cg3114 | ah | cysN | GTPases-Sulfate adenylate transferase subunit 1 | 0 | 3.42 | 0.48 | 4.4 | 1.4 | 3.2 | 6.2 | 4.1 | 4.0 | 4.6 | 3.1 | 1.0 | DtxR, McbR*, CysR* |
76 | cg3115 | ah | cysD | 3-phosphoadenosine 5-phosphosulfate sulfotransferase (PAPS reductase) | 0 | 3.27 | 0.78 | 4.4 | 2.8 | 3.0 | 5.5 | 4.0 | 3.7 | 4.2 | 2.4 | 1.0 | DtxR, McbR*, CysR* |
77 | cg3116 | ah | cysH | Phosphoadenosine-Phosphosulfate Reductase | 0 | 2.98 | n.d. | - | -0.5 | - | 2.7 | 2.3 | 2.4 | - | - | - | DtxR, McbR*, CysR* |
78 | cg3117 | ai | cysX | Hypothetical protein | 0 | 3.50 | 1.08 | - | - | - | - | - | - | - | - | - | DtxR, McbR*, CysR* |
79 | cg3118 | ai | cysI | Sulfite reductase hemoprotein beta-component | 0 | 3.50 | 1.06 | 0.6 | 1.5 | 2.4 | 3.5 | 2.1 | -0.3 | - | - | - | DtxR, McbR, CysR* |
80 | cg3119 | cysJ | Probable NADPH-dependent Sulfite Reductase | 0 | 2.99 | 0.29 | 4.9 | 4.2 | 3.5 | 2.8 | 1.3 | 1.4 | 2.0 | 1.4 | - | DtxR, McbR*, CysR* | |
81 | cg3157 | Uncharacterized vancomycin resistance protein | 1 | 1.54 | 0.23 | - | - | - | 2.7 | 2.1 | 3.1 | 3.7 | -0.6 | -0.4 | |||
82 | cg3215 | glpQ1 | Putative glycerophosphoryl diester phosphodiesterase | 0 | 1.02 | n.d. | - | - | - | - | - | - | - | - | - | ||
83 | cg3219 | ldh | Anaerobic L-lactate DH | 0 | 1.83 | 0.12 | 5.1 | 3.1 | 4.8 | 4.3 | 1.3 | 2.3 | - | - | -0.4 | GlxR* | |
84 | cg3227 | lldD | Aerobic FMN-L-lactate DH | 0 | 1.14 | 0.45 | 1.2 | 2.1 | 0.7 | 5.2 | 4.1 | 4.0 | 1.5 | -0.6 | - | GlxR* | |
85 | cg3236 | msrA | Methionine sulfoxide reductase | 0 | 1.27 | 1.01 | - | - | -0.8 | - | - | - | - | - | - | ||
86 | cg3372 | Hypothetical membrane protein | 0 | 2.80 | -0.16 | - | - | - | 1.8 | - | - | -0.7 | - | - | McbR*, CysR* | ||
87 | cg3374 | ak | Putative NADH-dependent flavin oxidoreductase | 0 | 2.48 | n.d. | - | - | - | - | - | - | - | - | - | McbR*, CysR* | |
88 | cg3375 | ak | Putative NAD dependent dehydratase | 0 | 1.61 | n.d. | 1.5 | -0.8 | 0.8 | - | - | - | - | - | - | McbR*, CysR* | |
Genes repressed at pH 6 | |||||||||||||||||
1 | cg0148 | panC | Pantoate--beta-alanine ligase | 0 | -1.29 | -0.56 | -0.6 | 1.7 | -0.8 | - | - | - | - | - | - | ||
2 | cg0244 | a | Hypothetical membrane protein | 4 | -1.23 | -0.49 | - | - | - | - | - | - | - | - | - | ||
3 | cg0245 | a | Putative Moco sulfurase involved in sulphur metal clusters formation | 0 | -1.02 | -0.64 | - | - | - | - | - | - | - | - | - | ||
4 | cg0252 | Hypothetical membrane protein | 5 | -1.16 | -0.58 | - | - | - | - | - | - | - | - | - | |||
5 | cg0308 | Putative membrane protein | 4 | -1.34 | n.d. | - | - | - | - | - | - | - | - | - | |||
6 | cg0337 | whiB4 | Transcriptional regulator | 0 | -1.04 | 0.39 | - | - | - | - | - | - | - | - | - | ||
7 | cg0350 | glxR | Transcriptional regulator | 0 | -1.18 | -0.07 | 4.0 | 4.7 | 4.6 | 3.3 | 2.8 | 3.1 | -0.7 | -0.6 | 1.5 | ||
8 | cg0445 | c | sdhCD | Succinate dehydrogenase CD | 5 | -1.31 | 1.31 | - | - | - | 1.8 | 1.4 | 2.4 | 3.2 | 4.0 | 5.0 | RipA, DtxR, RamA*, RamB* |
9 | cg0446 | c | sdhA | Succinate dehydrogenase A | 0 | -1.08 | 1.47 | 1.0 | 2.7 | 1.7 | 6.7 | 7.0 | 9.0 | 8.5 | 9.0 | 9.9 | RipA, DtxR, RamA*, RamB* |
10 | cg0447 | c | sdhB | Succinate dehydrogenase B | 0 | -1.43 | 1.14 | - | -0.4 | - | 4.6 | 5.0 | 6.7 | 3.5 | 3.4 | 5.3 | RipA, DtxR, RamA*, RamB* |
11 | cg0465 | Conserved hypothetical membrane protein | 3 | -1.14 | n.d. | - | - | - | - | -0.2 | - | - | - | - | DtxR | ||
12 | cg0466 | Heme transport system, substrate binding subunit | 0 | -1.33 | n.d. | - | - | - | - | - | - | - | - | - | DtxR | ||
13 | cg0470 | d | Heme transport associated protein | 2 | -1.66 | n.d. | -0.6 | 1.9 | - | 3.5 | 3.8 | - | 3.3 | 3.6 | - | DtxR, LexA | |
14 | cg0471 | d | Heme transport associated protein | 1 | -1.30 | n.d. | - | - | - | - | -0.3 | - | 0.1 | 1.0 | - | DtxR, LexA | |
15 | cg0493 | Hypothetical protein | 0 | -1.05 | -0.41 | - | - | - | - | - | - | - | - | - | |||
16 | cg0563 | e | rplK | 50S ribosomal protein L11 | 0 | -1.28 | -0.59 | - | - | - | 0.9 | 0.7 | 0.8 | -0.9 | - | -0.6 | |
17 | cg0564 | e | rplA | 50S ribosomal protein L1 | 0 | -1.10 | -0.57 | 4.5 | 5.0 | 4.8 | 3.9 | 4.2 | 4.0 | 4.1 | 4.4 | 4.5 | |
18 | cg0572 | f | rplJ | 50S ribosomal protein L10 | 0 | -1.60 | -0.69 | 3.4 | 4.3 | 3.6 | 2.1 | 2.3 | 2.1 | 4.2 | 4.5 | 3.9 | |
19 | cg0573 | f | rplL | 50S ribosomal protein L7/L12 | 0 | -1.53 | -0.59 | 5.3 | 5.5 | 4.5 | - | 1.3 | 0.0 | 0.2 | 0.4 | 1.6 | |
20 | cg0582 | rpsG | 30S ribosomal protein S7 | 0 | -1.07 | -0.35 | 3.1 | 3.4 | 2.1 | 2.2 | 2.6 | 3.3 | 1.3 | 1.6 | 1.5 | ||
21 | cg0599 | rpsS | 30S ribosomal protein S19 | 0 | -1.09 | -0.51 | 1.7 | 2.2 | 1.1 | - | - | -0.3 | - | - | - | ||
22 | cg0601 | g | rpsC | 30S ribosomal protein S3 | 0 | -1.05 | -0.35 | 3.3 | 3.2 | 3.0 | 4.7 | 4.0 | 4.5 | 0.3 | 0.4 | 0.4 | |
23 | cg0602 | g | rplP | Ribosomal protein L16/L10E | 0 | -1.02 | -0.27 | 3.1 | 3.3 | 3.1 | 4.5 | 4.8 | 5.0 | 3.0 | 3.4 | 3.5 | |
24 | cg0603 | g | rpmC | 50S ribosomal protein L29 | 0 | -1.01 | -0.20 | - | -0.8 | - | - | - | - | - | - | - | |
25 | cg0604 | g | rpsQ | 30S ribosomal protein S17 | 0 | -1.18 | -0.21 | 3.3 | 3.2 | 2.8 | - | - | 0.0 | - | - | - | |
26 | cg0623 | h | ABC-type cobalt exporter unit | 8 | -1.05 | -1.35 | - | - | - | - | - | - | - | - | - | ||
27 | cg0624 | h | Hypothetical membrane protein | 2 | -1.09 | -1.09 | - | - | - | - | - | - | 1.3 | 1.6 | -0.4 | ||
28 | cg0625 | h | Putative terpene cylase or prenyltransferase subunit | 1 | -1.28 | -1.04 | - | 2.2 | 0.0 | 2.8 | 3.6 | 2.2 | - | -0.6 | -0.4 | ||
29 | cg0690 | i | groS | 10 kDa chaperonin | 0 | -1.77 | -0.02 | 4.1 | 4.3 | 4.7 | - | - | - | - | - | - | SigM* |
30 | cg0691 | i | groEL | 60 kDa chaperonin HSP60 | 0 | -2.19 | -0.11 | 4.0 | 3.4 | 3.8 | - | - | - | 1.2 | -0.6 | 1.1 | SigM* |
31 | cg0693 | i | groL1 | 60 kDa chaperonin1 Hsp60 | 0 | -1.47 | 0.02 | 5.6 | 5.8 | 5.8 | 1.8 | 0.7 | 1.8 | 2.5 | 1.7 | 1.6 | |
32 | cg0748 | ABC-type Fe3+-siderophores transport systems, periplasmic components | 0 | -1.07 | -2.14 | -0.3 | 1.3 | - | 1.2 | 0.7 | - | 0.1 | -0.6 | - | DtxR | ||
33 | cg0752 | Putative flotillin like protein | 1 | -1.55 | -0.47 | 0.6 | 2.7 | 1.6 | 3.4 | 2.3 | 1.8 | 4.4 | 4.7 | 3.4 | |||
34 | cg0760 | prpB2 | Methylisocitrate lyase 2 | 0 | -1.54 | -0.80 | - | 3.2 | 0.9 | -0.4 | 0.8 | - | - | - | - | ||
35 | cg0762 | prpC2 | 2-methylcitrate synthase 2 | 0 | -1.39 | n.d. | - | 1.7 | 0.8 | - | - | - | - | - | - | ||
36 | cg0832 | ABC-type transporter, permease components | 5 | -1.33 | -0.40 | - | - | - | -0.4 | - | - | - | 1.0 | 1.1 | |||
37 | cg0834 | ABC-type transporter, periplasmic component | 0 | -2.46 | -0.03 | 1.6 | 3.4 | 2.7 | 2.5 | 3.6 | 3.7 | 2.9 | 4.2 | 4.1 | LexA | ||
38 | cg0842 | Putative DNA helicase | 0 | -1.03 | n.d. | - | - | - | - | - | - | - | - | - | |||
39 | cg0898 | pdxS | Pyridoxal biosynthesis lyase pdxS | 0 | -1.09 | -0.61 | 4.6 | 5.0 | 4.3 | - | - | - | -0.7 | - | - | LexA, PdxR | |
40 | cg0952 | o | mctB | putative monocarboxylate transporter subunit | 2 | -2.55 | -1.32 | - | 0.5 | - | 2.4 | 4.7 | 4.1 | - | 2.1 | -0.6 | |
41 | cg0953 | o | mctC | monocarboxylate transporter | 13 | -2.44 | -1.01 | - | 3.0 | -0.2 | 1.9 | 4.7 | 4.7 | 3.2 | 4.5 | 3.2 | |
42 | cg0961 | Homoserine acetyltransferase | 0 | -1.70 | n.d. | - | - | - | - | - | - | - | - | - | |||
43 | cg1072 | rplY | 50S ribosomal protein L25 | 0 | -1.26 | -0.49 | 0.7 | 1.1 | 0.6 | - | - | - | - | - | -0.4 | ||
44 | cg1108 | porC | Putative secreted protein | 0 | -1.11 | 0.06 | - | - | - | 0.8 | 2.3 | - | - | 1.0 | - | ||
45 | cg1122 | Hypothetical protein | 0 | -1.31 | 0.23 | - | -0.8 | -0.8 | 3.3 | 4.7 | 6.1 | 5.8 | 6.3 | 6.6 | |||
46 | cg1123 | greA | Transcription elongation factor | 0 | -1.21 | -0.14 | 2.0 | 0.4 | 2.4 | - | - | - | - | - | - | ||
47 | cg1167 | metS | putative methionine transporter subunit | 0 | -1.04 | -1.43 | - | - | - | - | - | - | -0.9 | - | -0.6 | ||
48 | cg1362 | t | atpB | F0F1-type ATP synthase a subunit | 6 | -1.35 | -0.85 | - | - | - | 2.7 | 3.2 | 3.8 | 5.8 | 6.0 | 5.5 | SigH* |
49 | cg1363 | t | atpE | F0F1-type ATP synthase c subunit | 2 | -1.60 | -0.88 | - | - | - | 4.4 | 5.0 | 3.6 | 5.4 | 6.6 | 6.4 | SigH* |
50 | cg1364 | t | atpF | F0F1-type ATP synthase b subunit | 1 | -1.52 | -0.96 | -0.6 | 0.5 | -0.8 | 4.5 | 4.8 | 4.9 | 4.9 | 5.4 | 4.3 | SigH* |
51 | cg1365 | t | atpH | F0F1-type ATP synthase delta subunit | 0 | -1.26 | -1.03 | 1.9 | 2.3 | 1.3 | 3.9 | 4.8 | 4.7 | 3.2 | 4.1 | 3.4 | SigH* |
52 | cg1366 | t | atpA | F0F1-type ATP synthase alpha subunit | 0 | -1.65 | -0.89 | 4.9 | 5.1 | 5.1 | 5.6 | 6.2 | 6.1 | 6.8 | 6.9 | 6.4 | SigH* |
53 | cg1367 | t | atpG | F0F1-type ATP synthase gamma chain | 0 | -1.71 | -1.11 | 1.1 | 4.2 | 3.4 | 3.3 | 4.9 | 4.7 | 4.0 | 4.0 | 2.5 | SigH* |
54 | cg1368 | t | atpD | F0F1-type ATP synthase beta chain | 0 | -1.72 | -0.94 | 5.3 | 5.5 | 5.4 | 5.7 | 5.8 | 5.6 | 6.3 | 6.0 | 5.7 | SigH* |
55 | cg1369 | t | atpC | F0F1-type ATP synthase epsilon chain | 0 | -1.09 | n.d. | 1.6 | 0.4 | 0.7 | - | - | -0.1 | 3.1 | 2.5 | 1.9 | SigH* |
56 | cg1436 | ilvN | Acetolactate synthase, subunit | 0 | -1.41 | -0.69 | 2.0 | 2.2 | 2.4 | 1.5 | 3.2 | 1.5 | -0.9 | -0.6 | -0.6 | ||
57 | cg1437 | ilvC | Ketol-acid reductoisomerase | 0 | -1.44 | -0.91 | 4.0 | 3.8 | 3.9 | 2.9 | 3.9 | 3.3 | -0.9 | 1.7 | -0.6 | ||
58 | cg1564 | u | rpmI | 50S ribosomal protein L35 | 0 | -1.04 | -0.31 | - | -0.8 | - | 1.6 | 1.4 | 2.4 | - | - | - | |
59 | cg1565 | u | rplT | 50S ribosomal protein L20 | 0 | -1.26 | -0.29 | 1.2 | 1.5 | -0.2 | - | -0.2 | - | - | - | - | |
60 | cg1579 | Hypothetical protein | 0 | -1.36 | -0.66 | - | - | - | - | - | - | - | - | - | |||
61 | cg1612 | Putative acetyltransferases | 0 | -1.32 | n.d. | - | - | - | - | - | - | - | - | - | |||
62 | cg1905 | y | Putative protein kinase | 0 | -1.33 | 0.72 | - | - | - | - | 0.7 | - | - | - | - | ||
63 | cg1906 | y | Putative protein phosphatase | 0 | -1.17 | 0.63 | - | - | - | - | -0.2 | - | - | - | - | ||
64 | cg1913 | Hypothetical protein | 0 | -1.19 | n.d. | - | - | - | - | - | - | - | - | - | |||
65 | cg1930 | z | Putative secreted serine protease | 0 | -1.18 | -3.26 | - | - | - | - | - | - | - | - | - | DtxR | |
66 | cg2136 | aa | gluA | ABC-type glutamate transporter, ATPase component | 0 | -1.36 | -0.07 | -0.6 | -0.5 | 0.8 | 1.9 | 4.3 | 3.8 | 2.2 | 3.4 | 2.7 | GlxR*, AmtR |
67 | cg2137 | aa | gluB | ABC-type glutamate transporter, substrate binding component | 0 | -1.38 | -0.39 | -0.6 | 2.7 | 1.3 | 2.4 | 3.3 | 3.5 | 4.9 | 5.5 | 5.1 | GlxR*, AmtR |
68 | cg2138 | aa | gluC | ABC-type glutamate transporter, permease component | 6 | -1.19 | -0.33 | - | - | - | 1.8 | 1.3 | 3.0 | - | - | -0.6 | GlxR*, AmtR |
69 | cg2167 | rpsO | 30S ribosomal protein S15 | 0 | -1.01 | -0.14 | 1.1 | 1.8 | 1.9 | -0.4 | - | - | - | -0.6 | 0.6 | ||
70 | cg2181 | ABC-type peptide transporter, periplasmic component | 0 | -2.20 | -0.53 | -0.2 | 3.5 | 1.5 | 2.8 | 4.0 | 4.1 | 3.9 | 5.7 | 5.6 | AmtR | ||
71 | cg2234 | ABC-type cobalamin/Fe3+-siderophores transporter, secreted component | 0 | -1.32 | n.d. | -0.6 | - | - | -0.4 | 0.7 | - | -0.9 | -0.6 | - | DtxR, RamB* | ||
72 | cg2235 | rplS | 50S ribosomal protein L19 | 0 | -1.40 | -0.46 | 2.5 | 2.2 | 1.9 | 6.6 | 6.9 | 7.5 | 3.0 | 3.9 | 3.7 | ||
73 | cg2253 | rpsP | 30S ribosomal protein S16 | 0 | -1.14 | -0.34 | 4.1 | 4.7 | 4.0 | 1.2 | 1.3 | 2.5 | 1.6 | -0.6 | -0.4 | ||
74 | cg2467 | ac | ABC-type peptide transporter, substrate binding component | 0 | -1.21 | -0.17 | - | - | - | -0.4 | 2.8 | 2.8 | 1.4 | -0.6 | 2.1 | ||
75 | cg2470 | ac | ABC-type peptide transporter, substrate binding component | 0 | -1.66 | -0.36 | 0.7 | 2.2 | 1.2 | 1.2 | 1.3 | 0.0 | 2.8 | 3.4 | 3.4 | ||
76 | cg2559 | ad | aceB | Malate synthase G | 0 | -1.21 | n.d. | -0.6 | 4.7 | 2.0 | - | - | - | - | - | - | RamA, RamB |
77 | cg2560 | ad | aceA | Isocitrate lyase | 0 | -2.73 | -2.19 | - | 4.9 | 2.4 | - | -0.3 | - | - | - | - | RamA, RamB |
78 | cg2573 | rpsT | 30S ribosomal protein S20 | 0 | -1.33 | -0.56 | 2.8 | 3.3 | 2.1 | 2.7 | 2.7 | 3.5 | 1.6 | 1.4 | 1.2 | ||
79 | cg2603 | ndk | Nucleoside diphosphate kinase | 0 | -1.19 | -0.20 | 2.8 | 3.3 | 3.2 | - | - | - | - | - | - | ||
80 | cg2647 | tig | Trigger factor | 0 | -1.47 | -0.27 | 4.8 | 5.4 | 5.0 | - | - | - | - | - | - | ||
81 | cg2703 | ABC-type transporter, permease component | 6 | -1.90 | -0.32 | - | - | - | - | - | - | - | - | - | |||
82 | cg2705 | ABC-type transporter, periplasmic component | 0 | -1.68 | -0.28 | 4.9 | 7.0 | 5.8 | 6.9 | 7.7 | 8.0 | 6.8 | 7.6 | 7.4 | |||
83 | cg2840 | actA | Butyryl-CaA-acetate coenzyme A transferase | 0 | -1.67 | -0.01 | 6.4 | 7.1 | 7.6 | 3.4 | 4.9 | 3.2 | - | 2.0 | 0.4 | RamB* | |
84 | cg2953 | xylC | Benzaldehyde dehydrogenase | 0 | -1.39 | 0.61 | 1.6 | 3.3 | 4.1 | 1.3 | 4.3 | 3.7 | - | - | 1.5 | GlxR* | |
85 | cg3011 | groL2 | 60 kDa chaperonin 2 (HSP60) | 0 | -2.20 | -0.44 | 5.9 | 6.7 | 6.8 | -0.4 | 1.7 | 3.5 | 2.2 | 2.4 | 3.0 | ||
86 | cg3048 | pta | Phosphate acetyltransferase | 0 | -1.07 | 0.16 | - | 1.7 | 2.3 | - | 2.9 | 2.8 | - | - | - | RipA, RamA, RamB | |
87 | cg3096 | NAD-dependent aldehyde dehydrogenases | 0 | -3.24 | 0.10 | 3.2 | 6.6 | 5.9 | 3.0 | 6.1 | 5.7 | - | 1.0 | 1.4 | |||
88 | cg3107 | adhA | Zn-dependent alcohol dehydrogenases | 0 | -1.97 | 0.06 | - | 2.9 | 1.8 | - | 5.6 | 4.9 | - | 3.7 | -0.4 | RamA, RamB, GlxR* | |
89 | cg3156 | htaA | secreted protein implicated in iron acquisition and transport | 0 | -2.50 | -2.76 | - | - | - | - | - | -0.3 | 2.7 | 5.7 | - | DtxR | |
90 | cg3195 | Flavin-containing monooxygenase | 0 | -2.23 | 0.32 | - | 2.2 | -0.8 | - | 4.9 | 3.9 | - | 3.7 | 2.1 | |||
91 | cg3212 | Hypothetical membrane protein | 0 | -1.92 | -0.50 | - | - | - | - | - | - | - | - | - | |||