Figure 5

A CHAOS sequence and the corresponding UCSC sequence. The two sequences between the two pairs of dotted lines are the CHAOS sequence and the UCSC sequence for the same human functional region. In more detail, in the left panel, assume S and E are the start position and the end position of the human region; A, B, C are the conserved human segments and A', B', C' are the corresponding mouse segments; the distance between S' and the left end of the segment A' is equal to the distance between S and the left end of the segment A; the distance between E' and the left end of the segment B' is equal to the distance between E and the left end of the segment B. Then the mouse sequence between S'E' is the CHAOS sequence.