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Figure 5 | BMC Genomics

Figure 5

From: Conservation of DNA-binding specificity and oligomerisation properties within the p53 family

Figure 5

Sequence logos for all p53 family proteins studied. The complete response element is shown, and bit values are plotted against sequence position. A value of 0 means all four nucleotides bind with the same affinity and there is no selectivity, whereas the value 2 stands for absolute selectivity for one nucleotide, with the other three being highly penalised. A measure of the total information content (or selectivity) of the protein can be calculated by summing up all individual bit scores at every position. The maximum theoretical value of information content for a 20-bp response element is 40 bit.

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