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Table 2 Comparison of DUB genes in human and zebrafish

From: Genome-wide loss-of-function analysis of deubiquitylating enzymes for zebrafish development

DUB Family Name

Extra DUB Genes in Zebrafish

Missing DUB Genes (Protein) in Zebrafish

Subtotal in Zebrafish

Subtotal in Human

USP

cyldb

USP6

51

58

 

usp2b

USP9X

  
 

usp9

USP9Y

  
 

usp12b

USP17

  
 

usp53

USP26

  
 

usp54b

USP29

  
 

unclassified (1)

USP35

  
 

unclassified (2)

USP41

  
 

unclassified (3)

USP50

  
  

USP51

  
  

USP52

  
  

USP55

  
  

#59 (DUB3)

  
  

#60

  
  

#61 (TL132-l)

  
  

#62 (TL132)

  

OTU

otud1l

OTUD6A

15

14

 

otud3

OTUBQ2

  
 

otud5b

OTUD1

  
 

zranb1b

   

UCH

  

4

4

MJD

 

ATXN3L

3

5

  

JOS3

  

JAMM

eif3hb

#89 (IFP38)

14

14

 

stambpb

#91

  

PPPDE

pppde1

 

4

n.a.

 

loc794838

   
 

pppde2a

   
 

pppde2b

   
  1. Through the in silico screen, 91 putative DUB genes were found in zebrafish, which were classified into 6 families. Details were summarized in the table. For the first 5 families (USP, OTU, UCH, MJD and JAMM), gene and protein names in human were based on Nijman et al., 2005 [4]. The human homologues of the PPPDE family were not studied in this work. n.a. stands for "not analyzed".