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Table 3 Functional groups enrichment with clusters under different evolution modes

From: Molecular evolution of the hyperthermophilic archaea of the Pyrococcus genus: analysis of adaptation to different environmental conditions

Functional group

Total clusters in group

All positively selected clusters on the Pyrococcus tree branches (as in Figure 2) †

Unique positively selected clusters on the Pyrococcus tree branches (as in Figure 2) †

Clusters not under positive selection †

  

a

b

c

d

a

b

c

d

 

Translation; ribosomal structure and biogenesis

168

32

45

48 ****

37

13

16

26 ****

19

55****

Transcription

62

13

25 ***

13

15

3

10

5

5

20**

Replication; recombination and repair

51

10

10

4*

6

6

6

3

5

26

Cell cycle control; cell division; chromosome partitioning

13

4

1*

1

1

2

0

0

1

8

Defense mechanisms

12

2

3

2

3

0

1

0

1

7

Signal transduction mechanisms

10

0

3

1

1

0

3

1

1

5

Cell wall/membrane/envelope biogenesis

19

2

1**

1*

2

2

1

1

2

13 *

Cell motility

11

3

2

3

2

1

2

1

1

4

Intracellular trafficking; secretion; vesicular transport

11

2

3

1

5 *

1

1

0

3

3*

Posttranslational modification; protein turnover; chaperones

32

6

8

2*

6

2

4

1

4

16

Energy production and conversion

78

13

14

10

12

5

9

8

5

40

Carbohydrate transport and metabolism

49

4*

10

6

8

2

6

2

6

28

Amino acid transport and metabolism

61

13

18

2***

10

7

9

2*

4

29

Nucleotide transport and metabolism

38

4

10

8

13 *

2

6

3

10 **

10**

Coenzyme transport and metabolism

58

12

17

8

11

5

9

4

5

23

Lipid transport and metabolism

15

1

2

0

3

0

2

0

2

10

Inorganic ion transport and metabolism

46

9

4**

4

4*

8 *

3

4

4

26

Secondary metabolites biosynthesis; transport and catabolism

7

2

1

0

2

2

0

0

1

3

Function unknown

170

22*

31*

17*

27

14

15

7*

17

96 **

Total

911

154

208

131

168

75

103

68

96

422

  1. † - Bold denotes cases with excess of clusters (*0.01 <p ≤ 0.05; **0.001 <p ≤ 0.01;; ***1 × 10-4 <p ≤ 0.001; ****p ≤ 1 × 10-4), italics denote cases with lack of clusters (*0.01 <p ≤ 0.05; **0.001 <p ≤ 0.01; ***1 × 10-4 <p ≤ 0.001; ****p ≤ 1 × 10-4).