Molecular evolution of the hyperthermophilic archaea of the Pyrococcus genus: analysis of adaptation to different environmental conditions

Table 4 Amino acid groups used in positive selection detection

Normalized van der Waals volume [83]
Tiny [0; 1.6]	G, A, S
Small [2.43; 3]	C, T, P, D, N, V
Medium [3.78; 4.77]	E, Q, I, L, M, H, K
Large [5.89; 8.08]	F, R, Y, W
Hydropathy index [84]
I [-4.5; -3.2]	R, K, N, D, Q, E, H
II [-1.6; -0.4]	P, Y, W, S, T, G
III [1.8; 2.8]	A, M, C, F
IV [3.8; 4.5]	L, V, I
Isoelectric point [85]
I [2.77; 3.22]	D, E
II [5.05; 6.3]	A, N, C, Q, G, I, L, M, F, P, S, T, W, Y, V
III [7.59; 10.76]	R, H, K
Hydrostatic pressure asymmetry index, PAI [14] & Hydrophobic parameter [86]
I	K, E, D, R, S, G
II	Q, C, T, N, H, A, P, M, I, F, L, V
III	Y, W
Polarity [87] & Hydrophobic parameter [86]
I	R, K, E, D
II	S, Q, N, G, H, P, T, A
III	C, M, V, Y, I, L, F, W
Polarity & Volume [87]
I	A, G, P, S, T
II	N, D, Q, E
III	R, H, K
IV	I, L, M, V, C
V	F, W, Y
Polarity [87] & Hydropathy index [84]
I	W, Y
II	P, T, G, S, A
III	I, L, V, F, C, M
IV	H, Q, K, R, N, E, D

ISSN: 1471-2164