Figure 4
From: Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice
Hes5 mRNA levels in 15 days old ADAM10 transgenic mice. Brains of 15 days old FVB/N (Wt), ADAM10 (AD) or ADAM10 dominant negative mutant (dn) overexpressing mice were analyzed for the amount of the Notch-1 target gene Hes5 mRNA. Quantification was performed by real-time RT-PCR. Values represent means ± SEM of four mice per group normalized to GAPDH mRNA (one way ANOVA, Dunnett's Multiple Comparison Test; p < 0.05, *).