Table 8 Substrates of ADAM10 [43] which are not regulated in mono-transgenic mice within the parameters given in the Methods section
From: Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice
Substrate groups | Symbol name of Mouse Gene |
|---|---|
CNS substrates of ADAM10 | App, Aplp2, Prnp, Efna2, L1cam, Cdh2, Pcdhg, Dll1, Notch1 |
Substrates of ADAM10 in inflammation | Cx3cl1, Cxcl16, Cdh5, F11r (JAM-A), Il6r, Fasl, Tnfrsf8 (CD30), Cd44 |
Growth factors and receptors cleaved by ADAM10 | Egfr, Egf, Btc, Erbb2 |