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Table 1 Higher ΔGas-5 increases the probability that shRNAs are functional.

From: Energy profile and secondary structure impact shRNA efficacy

shRNA ΔGas-5

Number

Functional Rate

>= -3.2

Functional

155

81.6% (155/190)

 

Not functional

35

 

<-3.2

Functional

66

66.7% (66/99)

 

Not functional

33

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