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Table 6 Gene ontology (GO) annotation summary for the orthologous AS gene set.

From: Genome-wide analysis of alternative splicing in cow: implications in bovine as a model for human diseases

A. Molecular function

%Bovine

(Ensembl)

% Bovine

genes

% Human

genes

% Mouse

Genes

Binding

33.5

69.86

70.43

69.53

Catalytic activity

14.9

33.22

32.67

32.8

Molecular transducer activity

4.42

11.07

11.58

11.47

Transporter activity

3.54

9.56

9.41

9.33

Transcription regulator activity

2.03

8.33

8.16

8.35

Enzyme regulator activity

2.8

6.68

6.39

6.44

Structural molecule activity

1.57

4.11

4.28

4.32

Other

0.94

3.08

3.34

3.07

B. Biological process

% Bovine

(Ensembl)

% Bovine

genes

% Human

genes

% Mouse

Genes

Cellular process

30.62

67.78

67.77

67.97

metabolic process

20.58

47.26

47.67

47.72

Biological regulation

12.99

31.74

31.89

31.96

Developmental process

10.9

26.08

26.44

26.79

Multicellular organismal process

10.53

24.2

24.35

24.75

Localization

9.67

23.43

22.69

23.21

Establishment of localization

8.08

20.12

19.74

19.82

Response to stimulus

6.22

15.33

16.01

16.93

Immune system process

2.14

5.25

5.84

5.88

Biological adhesion

2.63

5.37

5.35

5.59

Reproduction

1.51

3.82

3.96

4.03

Other

3.14

7.85

7.46

8.29

C. Cellular component

%Bovine

(Ensembl)

% Bovine

genes

% Human

genes

% Mouse

Genes

Cell

32.65

74.89

75.05

74.3

Cell part

32.65

74.89

75.05

74.3

Organelle

18.21

44.12

43.75

44.01

Organelle part

7.31

17.98

17.55

17.1

Macromolecular complex

5.88

15.95

15.33

15.55

Extracellular region

3.37

11.84

11.45

14.38

Extracellular region part

2.28

10.45

10.09

12.35

Membrane-enclosed lumen

1.86

5.76

5.63

5.88

Others

4.17

10.25

12.7

10.2