From: Alternative paths in HIV-1 targeted human signal transduction pathways
Uniprot id | Gene description | Gene Symbol | Properties |
---|---|---|---|
P07766 | CD3e molecule epsilon (CD3-TCR complex) | CD3E | HIV-1 target according to Group 1, Group 2 and predictions, known drug target |
Q13094 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | LCP2 | HIV-1 target according to predictions, siRNA protein |
P04234 | CD3d molecule delta (CD3-TCR complex) | CD3D | HIV-1 target according to Group 1, Group 2 and predictions |
P19174 | phospholipase C gamma 1 | PLCG1 | HIV-1 target according to Group 2, and predictions |
O43561 | linker for activation of T cells | LAT | None |
O75791 | GRB2-related adaptor protein 2 | GRAP2 | None |
P01730 | CD4 molecule | CD4 | HIV-1 target according to Group 1, Group 2, predictions, and experts, siRNA protein |
P09693 | CD3g molecule gamma (CD3-TCR complex) | CD3G | HIV-1 target according to Group 1, Group 2, and predictions |
P43403 | zeta-chain (TCR) associated protein kinase 70kDa | ZAP70 | HIV-1 target according to Group 1, Group 2, and predictions, known drug target |
Q08881 | IL2-inducible T-cell kinase | ITK | Known drug target |
P06239 | lymphocyte-specific protein tyrosine kinase | LCK | HIV-1 target according to Group 1, Group 2, and predictions |
P20963 | CD247 molecule | CD247 | HIV-1 target according to Group 1, predictions and experts |