Figure 8From: A multi-species comparative structural bioinformatics analysis of inherited mutations in α-D-Mannosidase reveals strong genotype-phenotype correlationActive site of bovine lysosomal α-mannosidase. The Tris ligand (labeled Trs) is shown in orange, the Zn2+ ion in purple and all the active site residues in red (ball-and-stick representation). These active site residues represent a structural hot-spot region, for the lethal phenotype.Back to article page