Figure 2

Propensity for cleavage sites to occur in solvent accessible locations. A. Propensities for solvent accessibilities (Sp) were measured for 24-mer subsequences with or without caspase cleavage sites (labelled "cleavage sites" and "non-cleavage sites" respectively). B. Distribution of "cleavage sites" and "non-cleavage sites" subsequences to Sp bins. Each Sp bin (0.10, 0.20...1.00) was allocated a proportion of sequences with Sp scores falling within the bin range (0-0.10, 0.11-0.19...0.91-1.00).