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Table 1 Positive predictive values (PPV) of model prediction at various P-score cut-offs.

From: A multi-factor model for caspase degradome prediction

 

PPV (%)1

P-score

CASVM-Model

GraBCas-Model

0.00

21.25

6.73

0.05

21.25

6.73

0.10

21.25

6.73

0.15

21.52

6.73

0.20

21.79

6.79

0.25

22.37

7.08

0.30

23.61

7.25

0.35

23.53

8.06

0.40

24.19

9.62

0.45

27.78

10.79

0.50

32.61

13.39

0.55

31.58

12.77

0.60

39.29

18.64

0.65

53.85

24.14

0.70

80.00

30.77

0.75

100.00

42.86

  1. 1PPV calculations are limited to P-score cut-off of 0.75 as all predicted cleavage sites were eliminated beyond this point for both models. CASVM-Model and GraBCas-Model indicate the use of either CASVM or GraBCas at the first step of the model.
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BMC Genomics

ISSN: 1471-2164

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