Table 1 Analysis of communication pathways for Long Term Hematopoietic Stem Cells (LT-HSC)
Gene expressed in LT-HSC | Mean Intensity | Corresponding gene in stroma | Mean Intensity | NIH3T3 | Osteoblasts |
|---|---|---|---|---|---|
activin receptor IIB | 267 | bone morphogenetic protein 4 | 1335 | 66 | 252 |
bone morphogenetic protein 4 | 169 | bone morphogenetic protein receptor, type 1A | 497 | 274 | 384 |
chemokine (C-X-C motif) receptor 4 | 372 | chemokine (C-X-C motif) ligand 12 | 12222 | 23 | 798 |
epidermal growth factor receptor | 149 | epiregulin | 422 | 288 | 153 |
insulin-like growth factor 2 | 105 | insulin-like growth factor 2 receptor | 535 | 1772 | 1704 |
Integrin alpha 4 | 1675 | junction adhesion molecule 2 | 201 | 16 | 26 |
integrin beta 1 (fibronectin receptor beta) | 307 | junction adhesion molecule 2 | 201 | 16 | 26 |
integrin beta 2 | 558 | junction adhesion molecule 3 | 152 | 42 | 204 |
jagged 2 | 222 | Notch gene homolog 3 (Drosophila) | 367 | 161 | 48 |
oncostatin M | 115 | oncostatin M receptor | 1151 | 1349 | 131 |
epidermal growth factor receptor | 149 | transforming growth factor alpha | 261 | 13 | 21 |
Integrin alpha 4 | 1675 | vascular cell adhesion molecule 1 | 692 | 182 | 929 |
integrin beta 1 (fibronectin receptor beta) | 307 | vascular cell adhesion molecule 1 | 692 | 182 | 929 |
integrin beta 7 | 329 | vascular cell adhesion molecule 1 | 692 | 182 | 929 |
kinase insert domain protein receptor | 311 | vascular endothelial growth factor A | 179 | 1006 | 169 |