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Figure 4 | BMC Genomics

Figure 4

From: Transcriptomic changes arising during light-induced sporulation in Physarum polycephalum

Figure 4

Interaction of the Most Upregulated and Downregulated Transcripts with the Actin Cytoskeleton. The conceptual network was predicted using the Cytoprophet module of Cytoscape [24–26], and therefore is solely based on information included on specialized interaction databases. Input transcripts included those from the top up- and down- regulated transcripts (Tables 2 and 3), and cDNAs taken from the previous interaction network (Figure 3). A significant probability of interaction (P-value > 0.9) is indicated as a thick edge. Node colors follow the same convention as in Figure 3, and hit count data can be found in Tables 2 and 3. This network includes 64 interactions (33 with P > 0.9) between 38 gene products. Genes without Cytoprophet-predicted interactions are not included, except for two interactions with Actin-P that were not predicted by Cytoprophet but that can be found in the literature (indicated with arrows). Interestingly, the previously featured network (Figure 3) connects the two groups of up- and downregulated transcripts in this figure. However, as Cytoprophet gathers experimental interaction data from specialized databases, some interactions depicted in Figure 3 are not shown (for example between POLB and ACTINP), because this data is not present on those source databases used by Cytoprophet for prediction.

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