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Table 2 List of putative differentially expressed gene clusters

From: Digital gene expression analysis of two life cycle stages of the human-infective parasite, Trypanosoma brucei gambiense reveals differentially expressed clusters of co-regulated genes

Up-regulated in bloodstream forms

Gene Accession ID

Protein ID

P -value

average fold change BSF/PCF

differentially expressed gene cluster 1

Tb11.01.6210

procyclin-associated gene 2-like protein, putative

0.00000

89.74

Tb11.01.6220

procyclin-associated gene 4 (PAG4) protein, putative

0.00000

73.35

Tb11.01.6230

expression site-associated gene 2 (ESAG2) protein, putative

0.00000

74.77

Tb11.01.6240

expression site-associated gene (ESAG) protein, putative

0.00001

40.70

Tb11.01.6250

expression site-associated gene (ESAG) protein, putative

0.00000

59.76

putative differentially expressed gene cluster 2

Tb10.70.1280

hypothetical protein, conserved

0.00014

17.69

Tb10.70.1290

hypothetical protein, conserved

0.00000

94.86

Tb10.70.1300

procyclin-associated gene 2 (PAG2) protein, putative

0.00185

14.05

Tb10.70.1310

procyclin-associated gene 1 (PAG1) protein, putative

0.00000

122.36

putative differentially expressed gene cluster 3

Tb927.1.4880

hypothetical protein, unlikely

0.00025

22.72

Tb927.1.4890

expression site-associated gene 2 (ESAG2) protein, putative

0.00000

634.48

Tb927.1.4900

expression site-associated gene 11 (ESAG11) protein, putative

0.00017

21.92

putative differentially expressed gene cluster 4

Tb927.1.5100

expression site-associated gene 2 (ESAG2) protein, putative

0.00000

270.71

Tb927.1.5110

expression site-associated gene 11 (ESAG11) protein, putative

0.14722

2.80

Tb927.1.5120

expression site-associated gene (ESAG) protein, putative

0.00005

38.10

Tb927.1.5130

hypothetical protein, unlikely

0.57653

1.17

Tb927.1.5160

hypothetical protein

0.00005

23.47

Tb927.1.5180

hypothetical protein

0.00003

29.84

Up-regulated in procyclics

Gene Accession ID

Protein ID

P -value

average fold change PCF/BSF

putative differentially expressed gene cluster 5

Tb927.1.2230

calpain-like protein fragment, putative

0.00007

4.13

Tb927.1.2240

hypothetical protein, unlikely

0.00000

7.92

Tb927.1.2250

hypothetical protein, unlikely

0.00010

4.04

  1. Differentially expressed gene clusters were defined as two or more contiguous genes, which were significantly differentially expressed at the 0.2 FDR. The gene accession identification number, protein description and average fold change is given for each gene.
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BMC Genomics

ISSN: 1471-2164

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