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Table 3 Orthologs between P. falciparum and three rodent malaria parasite species.

From: Defining species specific genome differences in malaria parasites

 

Pb vs. Py

Pb vs. Pc

Pc vs. Py

Py vs. Pf

Pb vs. Pf

Pc vs. Pf

'Core' set

4188

4188

4188

4188

4188

4188

<3 RMP orthologs

-

-

-

226

234

215

RMP specific

1485

-

1448

-

-

-

Total

5673

4188

5636

4414

4422

4403

Current set

3153

4641

3318

3375

3890

3842

Potential 'Core' set

4578

4578

4578

4578

4578

4578

Potential total

6063

4578

6026

4578

4578

4578

  1. Summary table of orthologs between P. falciparum and the three rodent parasite species. The 'core' set represent orthologs common in all four species defined via hybridization and bioinformatics information. Other gene set combinations were taken from the remaining permutations of genes generated from those with at least 2 RMP orthologs as well as the rodent parasite specific genes. The total number of orthologous pairs is the sum of the core genes with the other respective gene permutations while the current set denotes the status quo [25]. The potential total indicates the theoretical maximum of common genes as there is strong suggestion that a P. falciparum gene with at least one RMP ortholog can potentially be orthologous to all three RMP species.