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Table 3 Signature miRNAs and their predicted targets in the opposite prognostic group.

From: Pediatric primary central nervous system germ cell tumors of different prognosis groups show characteristic miRNome traits and chromosome copy number variations

miRNA

Mapping

Intragenic

Predicted Targets

p value

142-5p

17q22

 

ADAMTS5, BCHE, DCHS1, FIGN, FLJ10357, FLRT2, FZD7, HDAC4, MEIS2, NRP1, PDGFRA, PTPRD, RUNX1T1, SGCD, SVIL

2.09E-10

146a

5q33.3

 

C5orf23, PTGFRN, RPESP, RUNX1T1, SRR, THRB

5.89E-07

let-7e

19q13.43

 

(NA)

(NA)

26a

3p22.2

CTDSPL

ATP11C, C7orf42, CREBL2, DNAJA2, FRAT2, NFE2L3, NUP50, TFAP2C, WAPAL, ZNF655

4.23E-07

133b

6p12.2

 

(NA)

(NA)

181c

19p13.12

 

C17orf63, EPB41, NMT1

1.18E-03

154

14q32.2

 

(NA)

(NA)

218

4p15.31

*SLIT2

NUP50, SFMBT1, WDR66, WNT2B, ZDHHC23, ZNF313

1.82E-02

335

7q32.2

 

N4BP1, PHTF2, SLC45A3, WAPAL

3.34E-04

376a

14q32.31

 

BNC1, MAN1C1

1.45E-02

410

14q32.31

 

AGPAT7, DLG3, NMT1, OSBPL3, RGS16, ROD1, ZNRF2

2.27E-04

433

14q32.2

RTL1

PCCB, WAPAL

4.50E-02

503

Xq26.3

 

CREBL2, DNAJA2, KIAA1333, MBP, N4BP1, NUP50, PAFAH1B1, RNF138, WNT2B

1.41E-07

539

14q32.2

 

CCDC88A, FRAT2, LBA1, MYCL1, PSME3, SNAP29, WAPAL, XPO6

4.75E-05

543

14q32.31

 

ARFGEF2, ATP11C, CSNK1D, CTF8, OSBPL3, PAFAH1B1, PPTC7, RNF138, SDF2L1

2.38E-05

  1. NA: No miRNA target could be found in the opposite group.
  2. Underlined: Genes targeted by 2 microRNAs.
  3. In bold and underlined: Genes targeted by more then 2 microRNAs.