Figure 5

RNASeq-based expression comparison between random regions, UCEs, p300-bound region and coding exons. Ultraconserved elements present polyA+ RNASeq based expression levels which are significantly different from random non-coding regions as well as from coding regions, but not from p300 bound regions. Analysis of RNASeq data derived from mouse brain (A. Mortazavi et al, 2008) on several types of genomic regions, i.e. ultraconserved elements (red), randomized set of p300 bound regions (blue, Pennacchio et al, 2009), in vivo tested enhancer regions bound by p300 (green, Pennacchio et al, 2009), random non coding regions in the genome (white) and random coding exons (black).