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Table 5 Respiration deficient mutant formation in yeast cultures grown for 24 h in YPD medium containing indicated concentrations of CTBT

From: Chemogenomic and transcriptome analysis identifies mode of action of the chemosensitizing agent CTBT (7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine)

Strain CTBT (μg/ml) Petite mutants (%)
BY4741 0 0.2
  2 0.2
  4 0.5
sod1Δ 0 0.1
  0.25 0.6
sod2Δ 0 0.1
  0.25 31.7
  1. The results are means of two experiments.