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Table 5 Respiration deficient mutant formation in yeast cultures grown for 24 h in YPD medium containing indicated concentrations of CTBT

From: Chemogenomic and transcriptome analysis identifies mode of action of the chemosensitizing agent CTBT (7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine)

Strain

CTBT (μg/ml)

Petite mutants (%)

BY4741

0

0.2

 

2

0.2

 

4

0.5

sod1Δ

0

0.1

 

0.25

0.6

sod2Δ

0

0.1

 

0.25

31.7

  1. The results are means of two experiments.