Table 3 Classification of H. mustelae outer membrane proteins in relation to H. pylori OMPs
Gene | Protein length (AA) | Predicted MW (Da) | N-terminal signal motif†| C-term motif | FASTA Smith-Waterman identity* | Detected in proteome |
|---|---|---|---|---|---|---|
Hof-related OMPs | Â | Â | Â | Â | Â | Â |
HMU05640 | 456 | 51,804 | A?MDF | -YSF | 32.1% in 479 aa overlap with H. pylori HofB (HP1083) | Yes |
HMU05650 | 451 | 51,181 | A?VET | -YGF | 36.2% in 496 aa overlap with H. pylori HofF (HP0788) | Yes |
HMU10680 | 447 | 50,681 | A?ASS | -YFF | 29.3% in 474 aa overlap with H. pylori HofE (HP0782) | No |
Hop-related OMP | Â | Â | Â | Â | Â | Â |
HMU04150 | 189 | 20,863 | R?AYD? | -YSF | 34.7% in 170 aa overlap with HP0608 | No |
FecA-related OMP | Â | Â | Â | Â | Â | Â |
HMU11950 | 220 | 25,230 | ? | -ENP | No significant homologues | No |
Unclassified OMPS | Â | Â | Â | Â | Â | Â |
HMU00140 | 232 | 26,345 | G↓AGT | -FLF | No significant homologues | No |
HMU00150 | 252 | 28,374 | A↓KED | -IIF | No significant homologues | No |
HMU00180 | 242 | 27,650 | unclear | -YVF | No significant homologues | No |
HMU00690 | 208 | 22,360 | A↓EAI | -YTF | No significant homologues | No |
HMU00810 | 135 | 15,492 | A↓LVD | -IRY | No significant homologues | No |
HMU01060 | 316 | 34,414 | E↓ATK | -WYF | 39.7% in 194 aa overlap with HomD (HP1453) | No |
HMU02490 | 469 | 51,412 | A↓GKL | -YNF | No significant homologues | No |
HMU03240 | 394 | 32,308 | A↓IEN | -FYF | 34.5 in 281 aa overlap with HP0726 | No |
HMU03280 | 282 | 25,467 | unclear | -KFF | No significant homologues | No |
HMU03510 | 162 | 17,686 | V↓SPE | -VEF | No significant homologues | No |
HMU04930 | 899 | 98,821 | A↓YNP? | -WVF | 27.2% in 913 aa overlap with HomC (HP0373) | No |
HMU07910 | 873 | 98,252 | A↓NEI | -YHF | 32.0% in 443 aa overlap with HofD (HP0487) | No |
HMU09930 | 565 | 62,131 | V↓AGA | -YHW | 55% in 586 aa overlap with OmpP1 (HP0839) | No |
HMU13480 | 258 | 28,279 | A↓TKG? | -LIY | 32.0% in 259 aa overlap with HH_1629 | No |
HMU13600 | 190 | 21,548 | A↓MTL | -EAK | No significant homologues | Yes |
HMU13670 | 173 | 19,128 | A↓KTC | -NIK | No significant homologues | Yes |
HMU13270 | 236 | 27,193 | ↓ | -NHL | No significant homologues | No |
HMU00260 | 196 | 21,989 | A↓HAR? | -FVF | No significant homologues | No |
HMU07990 | 343 | 39,155 | A↓ENL | -FAF | 42.9% in 233 aa overlap with HP0694 | No |
HMU10040 | 167 | 18,839 | ↓ | -EGK | 50.9% in 163 aa overlap with HP1546 | No |
HMU01230 | 232 | 24,626 | A↓NTN | -YKF | 44.5% in 236 aa overlap with HH_0525 | No |