Figure 7
From: Myosin individualized: single nucleotide polymorphisms in energy transduction
Function-neutral candidate SNP missense substitutions in myosin heavy chain. The x-axis is the myosin 2× (MYH1) sequence from 1-400 in Panel A and 401-812 in Panel B. The y-axis indicates AHP in percent. Substitutions with AHP ≥ 0.5% are denoted by a vertical bar and by the residue substitution and sequence number in a horizontal label. The thick broken horizontal red line indicates myosin functional domain positions described in the text. Domain names are denoted with vertical labels. Converter domain (Panel B) SNP substitution P735S has an AHP showing 100% substitution in the 4 subpopulations tested suggesting the reference sequence is incorrect.